INT95904

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Context Info
Confidence 0.76
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 45
Total Number 48
Disease Relevance 26.17
Pain Relevance 1.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CD27)
Anatomy Link Frequency
B cell 7
memory B-cells 5
blood 2
lymphocytes 2
effector T cells 1
CD27 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 47 98.00 Very High Very High Very High
Inflammation 187 94.36 High High
chemokine 128 92.28 High High
Central nervous system 13 89.64 High High
cytokine 127 89.40 High High
Multiple sclerosis 42 86.88 High High
Osteoarthritis 19 85.68 High High
rheumatoid arthritis 71 84.48 Quite High
Demyelination 1 81.12 Quite High
intrathecal 14 71.92 Quite High
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 1881 99.96 Very High Very High Very High
Bacterial Infection 493 99.64 Very High Very High Very High
Disease 866 99.62 Very High Very High Very High
Infection 706 99.12 Very High Very High Very High
Juvenile Chronic Polyarthritis 16 98.00 Very High Very High Very High
Autoimmune Disease 133 95.72 Very High Very High Very High
Neurological Disease 16 95.24 Very High Very High Very High
Exanthema 101 94.52 High High
INFLAMMATION 184 94.36 High High
Syndrome 65 91.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Peripheral blood CD19+ lymphocytes were gated and stained for expression of CD27 in combination with CD20.
Gene_expression (expression) of CD27 in lymphocytes
1) Confidence 0.76 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.62 Pain Relevance 0
A positive family history was elicited in 8 cases (15%), and Human Leukocyte Antigen type B27 was positive in 42 cases (81%).
Gene_expression (positive) of Antigen type B27 in Leukocyte
2) Confidence 0.67 Published 2000 Journal Saudi Med J Section Body Doc Link 11369960 Disease Relevance 0 Pain Relevance 0
Within the group of SLE patients, the presence of serum anti-RNP antibodies (N = 13) was found to be associated with a higher frequency of CD27++/CD20?
Gene_expression (/) of CD27 associated with systemic lupus erythematosus
3) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.30 Pain Relevance 0
naïve B cell, and CD27++/CD20?
Gene_expression (/) of CD27 in B cell
4) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.26 Pain Relevance 0
Since immunosuppressive therapy may influence the presence of CD27++/CD20?
Gene_expression (presence) of CD27
5) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.89 Pain Relevance 0
Sizes of IgD+ CD38++ transitional B cell, CD27?
Gene_expression (Sizes) of CD27 in B cell
6) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.26 Pain Relevance 0
The absolute number of CD27++/CD20?
Gene_expression (/) of CD27
7) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.72 Pain Relevance 0
For the detection of CD27, CD20, and CD138 expressing B cells, a live gate was set on the CD19+ cell population.
Gene_expression (detection) of CD27 in B cells
8) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0 Pain Relevance 0
Increased mean frequencies of CD27++/CD20?
Gene_expression (frequencies) of CD27
9) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.68 Pain Relevance 0
On admission (day 0), both SLE patients had elevated frequencies and absolute numbers of CD27++/CD20?
Gene_expression (frequencies) of CD27 associated with systemic lupus erythematosus
10) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.93 Pain Relevance 0
A weak relationship between the number of CD27++ PCs and the occurrence of anti-ENA antibodies was also observed in a prior study (25).
Gene_expression (number) of CD27
11) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.90 Pain Relevance 0
Sizes of the CD27++/CD20?
Gene_expression (/) of CD27
12) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.58 Pain Relevance 0
On admission (day 0), both SLE patients had elevated frequencies and absolute numbers of CD27++/CD20?
Gene_expression (/) of CD27 associated with systemic lupus erythematosus
13) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.91 Pain Relevance 0
Since immunosuppressive therapy may influence the presence of CD27++/CD20?
Gene_expression (/) of CD27
14) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.88 Pain Relevance 0
Frequencies of CD27++/CD20?
Gene_expression (Frequencies) of CD27
15) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0 Pain Relevance 0
The mean frequency of CD27++/CD20?
Gene_expression (frequency) of CD27
16) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.37 Pain Relevance 0
Patients with systemic lupus erythematosus (SLE) exhibit an expanded population of CD27++ PCs, while the number of CD27?
Gene_expression (number) of CD27 associated with systemic lupus erythematosus
17) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.93 Pain Relevance 0
The absolute number of CD27++/CD20?
Gene_expression (/) of CD27
18) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.45 Pain Relevance 0
The mean frequency of CD27++/CD20?
Gene_expression (/) of CD27
19) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.37 Pain Relevance 0
In the healthy control group, the mean frequency of CD27++/CD20?
Gene_expression (/) of CD27
20) Confidence 0.66 Published 2007 Journal J Clin Immunol Section Body Doc Link PMC2039801 Disease Relevance 0.67 Pain Relevance 0

General Comments

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