INT95918

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Context Info
Confidence 0.24
First Reported 2001
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CYSLTR2) cellular_component (CYSLTR2) signal transducer activity (CYSLTR2)
Anatomy Link Frequency
blood 2
CYSLTR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory marker 3 86.48 High High
Inflammation 29 82.56 Quite High
Analgesic 3 25.00 Low Low
aspirin 8 5.00 Very Low Very Low Very Low
Inflammatory stimuli 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 35 86.48 High High
Rhinitis 16 82.72 Quite High
Nasal Polyps 24 56.32 Quite High
Chronic Sinusitis 24 5.00 Very Low Very Low Very Low
Disease 15 5.00 Very Low Very Low Very Low
Asthma 7 5.00 Very Low Very Low Very Low
Polyps 3 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low
Heart Rate Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Methods And Subjects: Different fractions of Harpagophytum extracts were tested in vitro in human whole blood samples for effects on basal and ionophore A23187-stimulated cysteinyl-leukotriene (Cys-LT) and thromboxane synthesis.
Regulation (effects) of Gene_expression (synthesis) of cysteinyl-leukotriene in blood
1) Confidence 0.24 Published 2001 Journal Clin. Pharmacol. Ther. Section Abstract Doc Link 11372004 Disease Relevance 0.08 Pain Relevance 0.04
On the other hand CysLT1 and CysLT2 mRNA levels were similar in CRS and normal mucosa, however significantly higher concentrations of CysLT1 compared to CysLT2 were observed in the CRS-NP group.


Regulation (similar) of Gene_expression (levels) of CysLT2 mRNA
2) Confidence 0.16 Published 2006 Journal Respir Res Section Body Doc Link PMC1481584 Disease Relevance 0.31 Pain Relevance 0.08

General Comments

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