INT95969

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Context Info
Confidence 0.34
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OPRD1, ABCB1) transport (ABCB1) ATPase activity (ABCB1)
transmembrane transport (ABCB1) cytoplasm (OPRD1) signal transducer activity (OPRD1)
Anatomy Link Frequency
fibroblast 1
OPRD1 (Homo sapiens)
ABCB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 100.00 Very High Very High Very High
opioid receptor 1 100.00 Very High Very High Very High
Opioid 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Tics 9 97.96 Very High Very High Very High
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analogues Dmt-Tic (2',6'-dimethyl-L-tyrosine-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) pharmacophore, a potent delta-opioid receptor antagonist, inhibited hMDR1 P-GP expressed in a G-185 fibroblast cell line in a manner similar to verapamil.
delta-opioid receptor Negative_regulation (inhibited) of P-GP in fibroblast associated with tics, antagonist and opioid receptor
1) Confidence 0.34 Published 2001 Journal Brain Res. Section Abstract Doc Link 11376603 Disease Relevance 0.75 Pain Relevance 0.21

General Comments

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