INT96038

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Context Info
Confidence 0.30
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.55
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Rasgrp1) cytosol (Rasgrp1) Golgi apparatus (Rasgrp1)
endoplasmic reticulum (Rasgrp1) plasma membrane (Rasgrp1) intracellular (Rasgrp1)
Rasgrp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid receptor 1 7 98.44 Very High Very High Very High
Dopamine 47 84.88 Quite High
Substantia nigra 9 56.96 Quite High
ischemia 2 50.00 Quite Low
COX2 1 10.00 Low Low
anesthesia 1 10.00 Low Low
dopamine receptor 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Movement Disorders 1 95.80 Very High Very High Very High
Dyskinesias 34 92.28 High High
Thyroid Disease 2 63.76 Quite High
Injury 2 61.36 Quite High
Hyperkinesis 5 60.08 Quite High
Hyperthyroidism 2 50.08 Quite High
Parkinson's Disease 6 50.00 Quite Low
Cv Unclassified Under Development 2 50.00 Quite Low
Reperfusion Injury 1 50.00 Quite Low
Disease 21 47.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Notably, the increased striatal TRH immunostaining that we observed was combined with increased immunostaining for CalDAG-GEFII but with decreased immunostaining for MOR1, both reliable markers of striosomes.
Positive_regulation (increased) of CalDAG-GEFII associated with opioid receptor 1
1) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978093 Disease Relevance 0.49 Pain Relevance 0.17
RESULTS: Cal I-1 significantly reduced I/R-mediated increases in urea, creatinine, gamma GT, AST, NAG, and FE(Na) and significantly improved C(Cr).
Positive_regulation (increases) of Cal I-1
2) Confidence 0.17 Published 2001 Journal Kidney Int. Section Body Doc Link 11380809 Disease Relevance 0.06 Pain Relevance 0

General Comments

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