INT96186

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Context Info
Confidence 0.53
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 8.54
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MLF1IP) nucleoplasm (MLF1IP) chromosome (MLF1IP)
nucleus (MLF1IP) cytoplasm (MLF1IP)
Anatomy Link Frequency
B-cells 1
nucleus 1
MLF1IP (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 13 95.60 Very High Very High Very High
Pain 5 90.60 High High
cva 2 77.04 Quite High
ischemia 2 76.48 Quite High
iatrogenic 3 68.08 Quite High
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epstein-barr Virus 81 100.00 Very High Very High Very High
Cancer 25 99.76 Very High Very High Very High
Lymphatic System Cancer 47 99.62 Very High Very High Very High
Disease 114 97.96 Very High Very High Very High
Viral Infection 13 97.92 Very High Very High Very High
Thyroiditis 117 95.76 Very High Very High Very High
Plasma Cell Granuloma 3 95.60 Very High Very High Very High
Autoimmune Hepatitis 1 93.56 High High
Infection 62 92.92 High High
Reprotox - General 1 1 90.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tumor cells were positive for CD 10, CD 20, CD 30, and Epstein-Barr virus (EBV) latent membrane protein 1 (LMP-1) and early region RNA (EBER).
Gene_expression (positive) of latent membrane protein 1 associated with cancer and epstein-barr virus
1) Confidence 0.53 Published 2003 Journal Int. J. Surg. Pathol. Section Abstract Doc Link 14615832 Disease Relevance 1.12 Pain Relevance 0.17
EBV-latent membrane protein-1 was expressed commonly, albeit often focally and weakly.
Gene_expression (expressed) of EBV-latent membrane protein-1 associated with epstein-barr virus
2) Confidence 0.34 Published 2001 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 11395549 Disease Relevance 1.53 Pain Relevance 0.21
Viral infection in B-cells usually remains latent, i.e., infectious virus is not produced, and is characterised by the expression of several viral proteins, notably EBV-encoded nuclear antigen (EBNA) 2 and latent membrane protein (LMP) 1, which are thought to orchestrate virus-induced immortalisation and proliferation of B-cells.
Gene_expression (expression) of latent membrane protein in B-cells associated with viral infection and epstein-barr virus
3) Confidence 0.04 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2853499 Disease Relevance 1.37 Pain Relevance 0.03
In-situ hybridization revealed positive signals in the nucleus of lymphoma cells, which also expressed latent membrane protein-1 [132].
Gene_expression (expressed) of latent membrane protein-1 in nucleus associated with lymphatic system cancer
4) Confidence 0.01 Published 2009 Journal Virol J Section Body Doc Link PMC2654877 Disease Relevance 2.82 Pain Relevance 0
LMP1 (Latent Membrane Protein 1) an essential EBV protein commonly expressed and associated with the pathogenesis of Hodgkin's disease [17] was also positively stained for in our case.
Gene_expression (expressed) of Latent Membrane Protein 1 associated with epstein-barr virus and disease
5) Confidence 0.01 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2117016 Disease Relevance 1.64 Pain Relevance 0

General Comments

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