INT96261

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Context Info
Confidence 0.02
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pik3cd, Plcg2) cytosol (Plcg2) cell differentiation (Pik3cd)
plasma membrane (Plcg2) kinase activity (Pik3cd) lipid metabolic process (Plcg2)
Pik3cd (Mus musculus)
Plcg2 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 3 99.14 Very High Very High Very High
opioid receptor 2 98.98 Very High Very High Very High
antinociception 7 98.38 Very High Very High Very High
Morphine 8 94.08 High High
Intracerebroventricular 1 46.08 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present findings suggest that the supraspinal antinociception induced by mu-opioid receptor agonist may be mediated, at least in part, by the activation of PLC gamma through the stimulation of PI3-Kinase modulated by G beta gamma subunit.
Positive_regulation (stimulation) of PI3-Kinase Positive_regulation (activation) of PLC gamma associated with antinociception, agonist and opioid receptor
1) Confidence 0.02 Published 2001 Journal Nihon Shinkei Seishin Yakurigaku Zasshi Section Abstract Doc Link 11400324 Disease Relevance 0 Pain Relevance 1.21

General Comments

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