INT96301

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Context Info
Confidence 0.14
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnf) extracellular space (Tnf) extracellular region (Tnf)
plasma membrane (Tnf) intracellular (Tnf) extracellular matrix organization (Tnf)
Anatomy Link Frequency
peritoneal macrophages 2
Olr1742 (Rattus norvegicus)
Tnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 2 95.08 Very High Very High Very High
opioid receptor 5 92.72 High High
antagonist 1 90.64 High High
agonist 2 89.64 High High
Intracerebroventricular 1 87.00 High High
Morphine 1 79.80 Quite High
MU agonist 1 79.12 Quite High
mu opioid receptor 1 65.68 Quite High
Inflammation 1 29.44 Quite Low
cytokine 1 28.40 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We demonstrated that CGPM-9 enhanced rat thymic lymphocyte proliferative response to concanavalin A (2.85- to 5.5-fold increases), and suppressed LPS-induced nitric oxide (67 to 72 percent reduction) and TNF-alpha production (46 percent reduction) by peritoneal macrophages, compared with untreated control.
CGPM-9 Negative_regulation (suppressed) of Gene_expression (production) of TNF-alpha in peritoneal macrophages
1) Confidence 0.14 Published 2001 Journal Life Sci. Section Abstract Doc Link 11405238 Disease Relevance 0 Pain Relevance 0.74

General Comments

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