INT96318

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Context Info
Confidence 0.59
First Reported 2001
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.35
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (gr)
gr (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 7 100.00 Very High Very High Very High
antidepressant 6 98.76 Very High Very High Very High
Hippocampus 4 92.92 High High
corticosteroid 3 91.16 High High
Disease Link Frequency Relevance Heat
Stress 24 100.00 Very High Very High Very High
Sprains And Strains 8 98.32 Very High Very High Very High
Urological Neuroanatomy 2 58.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, chronic treatment with the antidepressant drug fluoxetine during adolescence or adulthood reversed the effect of early life stress on adult GR mRNA expression.
Regulation (effect) of Transcription (expression) of GR associated with stress, antidepressant and fluoxetine
1) Confidence 0.59 Published 2010 Journal Dev. Neurosci. Section Abstract Doc Link 20453467 Disease Relevance 1.28 Pain Relevance 0.18
In contrast to the strain-independent effect of early life stress on GR expression, however, changes in egr-1 expression occurred only in Balb/c mice, and unlike the biphasic developmental changes in GR mRNA expression, egr-1 mRNA was decreased throughout postnatal development.
Regulation (changes) of Transcription (expression) of GR associated with stress and sprains and strains
2) Confidence 0.59 Published 2010 Journal Dev. Neurosci. Section Abstract Doc Link 20453467 Disease Relevance 1.07 Pain Relevance 0.19
We examined the effects of short term (9 days) treatment with fluoxetine (10 mg/kg) and venlafaxine (10 mg/kg) on hippocampal mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) mRNA expression and spatial memory in adult rats.
Spec (examined) Regulation (effects) of Transcription (expression) of GR associated with fluoxetine
3) Confidence 0.03 Published 2001 Journal Neurosci. Lett. Section Abstract Doc Link 11406320 Disease Relevance 0 Pain Relevance 0.59

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