INT96402

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Context Info
Confidence 0.02
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PTGS2, TBXAS1) endoplasmic reticulum (PTGS2, TBXAS1) isomerase activity (TBXAS1)
enzyme binding (PTGS2) protein complex (PTGS2) cytoplasm (PTGS2)
Anatomy Link Frequency
PGE2 1
PTGS2 (Homo sapiens)
TBXAS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 96.16 Very High Very High Very High
COX-2 inhibitor 1 94.48 High High
Inflammation 4 81.00 Quite High
Inflammatory response 1 75.00 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 84.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These apparent COX-isotype dependencies of TXA2 and PGE2 synthesis can be explained by differences in the affinities of TXA synthase and PGE synthase for the common substrate, PGH2.
PGH2 Binding (affinities) of TXA synthase in PGE2
1) Confidence 0.02 Published 2001 Journal Inflamm. Res. Section Abstract Doc Link 11409487 Disease Relevance 0.32 Pain Relevance 0.26

General Comments

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