INT96420

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Context Info
Confidence 0.49
First Reported 1999
Last Reported 2011
Negated 2
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 3.70
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (NT5E) plasma membrane (NT5E) DNA metabolic process (NT5E)
cytoplasm (NT5E)
Anatomy Link Frequency
endothelial cells 1
bone marrow 1
mesenchymal cells 1
NT5E (Homo sapiens)
Pain Link Frequency Relevance Heat
Myofascial pain syndrome 4 98.64 Very High Very High Very High
Inflammatory stimuli 20 92.96 High High
Inflammation 133 89.80 High High
cva 72 88.76 High High
rheumatoid arthritis 16 87.68 High High
ischemia 9 83.16 Quite High
Multiple sclerosis 2 82.04 Quite High
cytokine 96 80.96 Quite High
chemokine 13 76.80 Quite High
Inflammatory mediators 11 72.88 Quite High
Disease Link Frequency Relevance Heat
Disease 20 99.96 Very High Very High Very High
Adult Respiratory Distress Syndrome 10 99.90 Very High Very High Very High
Temporomandibular Joint Disorders 4 98.64 Very High Very High Very High
Pancreatitis 76 97.12 Very High Very High Very High
INFLAMMATION 155 92.64 High High
Pneumonia 16 89.80 High High
Subarachnoid Hemorrhage 70 88.76 High High
Rheumatoid Arthritis 17 87.68 High High
Obesity 12 87.60 High High
Brain Hemorrhage 1 83.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dentists need to be alert to the possibility of primary ENT disorders in patients who present with TMD symptoms, as should ENT physicians be familiar with the clinical presentation of TMD, especially in those patients who present with ENT symptoms but no sign of ENT disease.
Neg (no) Positive_regulation (sign) of ENT associated with myofascial pain syndrome and disease
1) Confidence 0.49 Published 1999 Journal Aust Endod J Section Abstract Doc Link 11411075 Disease Relevance 0.54 Pain Relevance 0.37
Both MSCs were positive for CD73, CD90, CD105, CD166 and negative for CD34, CD45, CD19 and HLA-DR (Figure 2, Figure S1).
Positive_regulation (positive) of CD73
2) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2814860 Disease Relevance 0.32 Pain Relevance 0.11
The cells showed no expression of CD45, CD20/CD79a, or HLA-DR, but were positive for CD73, CD90, and CD105 in passage three and six (Table 4).
Positive_regulation (positive) of CD73
3) Confidence 0.12 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875643 Disease Relevance 0.41 Pain Relevance 0.20
After 2 passages, when cells are positive for mesenchymal markers (CD105, CD90, CD73, CD166) and negative for hematopoietic/endothelial markers (HLA-Dr, CD34, CD45), we differentiated them with the neurogenic medium as previously described [14].
Positive_regulation (positive) of CD73
4) Confidence 0.11 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2358905 Disease Relevance 0.05 Pain Relevance 0.04
At flow cytometry analysis AM-hMSCs showed an immunophenotypical profile, i.e., positive for CD105, CD73, CD29, CD44, CD166 and negative for CD14, CD34, CD45, consistent with that reported for bone marrow-derived MSCs.
Positive_regulation (positive) of CD73 in bone marrow
5) Confidence 0.07 Published 2007 Journal BMC Dev Biol Section Abstract Doc Link PMC1810523 Disease Relevance 0 Pain Relevance 0
TPN should only be used in patients unable to tolerate EN.
Neg (unable) Positive_regulation (tolerate) of EN
6) Confidence 0.06 Published 2011 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2929521 Disease Relevance 0.72 Pain Relevance 0
However, markers reported to be present on mesenchymal cells SSEA4 and CD73 (Figure 2) did not change drastically on priming with either IFN?
Positive_regulation (mesenchymal cells) of CD73 in mesenchymal cells
7) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2814860 Disease Relevance 0.41 Pain Relevance 0.21
treatment ameliorated vascular leakage in ALI via upregulation of 5'-nucleotidase (CD73) on pulmonary endothelial cells [25].
Positive_regulation (upregulation) of CD73 in endothelial cells associated with adult respiratory distress syndrome
8) Confidence 0.02 Published 2010 Journal Crit Care Section Body Doc Link PMC2945141 Disease Relevance 1.13 Pain Relevance 0.45
Finally, reduced ammonia production by AMP deaminase may have also reflected the activation of alternative routes of AMP metabolism, including 5'nucleotidase.
Positive_regulation (activation) of nucleotidase
9) Confidence 0.01 Published 2005 Journal BMC Physiol Section Body Doc Link PMC1187899 Disease Relevance 0.13 Pain Relevance 0

General Comments

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