INT96424

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Context Info
Confidence 0.69
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 9
Disease Relevance 6.34
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Bmp2) growth (Bmp2) extracellular region (Bmp2)
embryo development (Bmp2) protein complex (Bmp2) cytoplasm (Bmp2)
Anatomy Link Frequency
schwann cell 2
muscles 1
trigeminal nerve 1
Bmp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Trigeminal neuralgia 8 99.76 Very High Very High Very High
fifth nerve 8 99.36 Very High Very High Very High
Pain 4 61.56 Quite High
Peripheral nervous system 3 48.44 Quite Low
anesthesia 9 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 8 99.76 Very High Very High Very High
Nerve Sheath Neoplasms 8 99.56 Very High Very High Very High
Tendinopathy 52 99.06 Very High Very High Very High
Neurilemmoma 12 98.88 Very High Very High Very High
Calcification 114 98.80 Very High Very High Very High
Malignant Neoplastic Disease 8 97.80 Very High Very High Very High
Tendon Injuries 36 92.44 High High
Injury 61 90.40 High High
Neurodegenerative Disease 1 80.92 Quite High
Hyperplasia 4 78.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study aimed to study the spatial and temporal expression of BMP-2 protein and mRNA in both animal models.
Transcription (expression) of BMP-2 protein
1) Confidence 0.69 Published 2009 Journal J Orthop Surg Res Section Body Doc Link PMC2725034 Disease Relevance 1.19 Pain Relevance 0.06
The mRNA transcriptions of BMP-2, 3, 4 and 5 in 10 cases of schwannoma, three cases of malignant schwannoma and two cases of trigeminal neuralgia were detected using an in situ hybridization technique.
Transcription (transcriptions) of BMP-2 associated with malignant neoplastic disease, neurilemmoma and trigeminal neuralgia
2) Confidence 0.68 Published 2001 Journal Histol. Histopathol. Section Abstract Doc Link 11642720 Disease Relevance 0.74 Pain Relevance 0.25
Our results demonstrated that the myelin sheaths of Schwann cell from the peripheral neuroectomy of trigeminal neuralgia positively expressed mRNA of BMP-2, 3, 4, and 5.
Transcription (expressed) of BMP-2 in Schwann cell associated with trigeminal neuralgia
3) Confidence 0.68 Published 2001 Journal Histol. Histopathol. Section Abstract Doc Link 11642720 Disease Relevance 0.78 Pain Relevance 0.28
Transcriptional mRNA of BMP-2, 3, 4 and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors.
Transcription (Transcriptional) of BMP-2 in trigeminal nerve associated with nerve sheath neoplasms and fifth nerve
4) Confidence 0.68 Published 2001 Journal Histol. Histopathol. Section Title Doc Link 11642720 Disease Relevance 0.74 Pain Relevance 0.25
mRNA expression of BMP-2
Transcription (expression) of BMP-2
5) Confidence 0.53 Published 2009 Journal J Orthop Surg Res Section Body Doc Link PMC2725034 Disease Relevance 0.65 Pain Relevance 0
For the collagenase-induced calcific tendinopathy group, there was significant increase in mRNA expression of BMP-2 compared to that at the contralateral side at week 2 (p = 0.046) (Figure 2A).
Transcription (expression) of BMP-2 associated with calcification and tendinopathy
6) Confidence 0.53 Published 2009 Journal J Orthop Surg Res Section Body Doc Link PMC2725034 Disease Relevance 0.69 Pain Relevance 0
There was also increase in mRNA expression of BMP-2 at week 4 but it was marginally insignificant (p = 0.068).
Transcription (expression) of BMP-2
7) Confidence 0.53 Published 2009 Journal J Orthop Surg Res Section Body Doc Link PMC2725034 Disease Relevance 0.70 Pain Relevance 0
Our results demonstrated that the myelin sheaths of schwann cell from the peripheral neuroectomy of trigeminal neuralgia were positively expressing mRNA of BMP-2, 3, 4 and 5.
Transcription (expressing) of BMP-2 in schwann cell associated with trigeminal neuralgia
8) Confidence 0.50 Published 2001 Journal Kaohsiung J. Med. Sci. Section Abstract Doc Link 11411255 Disease Relevance 0.86 Pain Relevance 0.28
Human BMP-2 and BMP-7 mRNA expression in muscles electroporated with pCAGGS-BMP-2 and pCAGGS-BMP-7
Transcription (expression) of BMP-2 in muscles
9) Confidence 0.12 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1557501 Disease Relevance 0 Pain Relevance 0

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