INT96523

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Context Info
Confidence 0.69
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 3.78
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Chka) cytoplasm (Chka)
Anatomy Link Frequency
covering 1
plasma 1
muscle 1
gastrocnemius 1
chest 1
Chka (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 81.84 Quite High
Pain 7 75.92 Quite High
Pain threshold 1 73.44 Quite High
corticosteroid 3 34.40 Quite Low
Central nervous system 1 19.64 Low Low
chemokine 5 5.00 Very Low Very Low Very Low
chest pain 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myalgia 4 99.58 Very High Very High Very High
Disease 22 99.00 Very High Very High Very High
Leukemia 7 98.20 Very High Very High Very High
Coronary Heart Disease 5 98.12 Very High Very High Very High
Lymphatic System Cancer 122 97.82 Very High Very High Very High
Natriuresis 2 97.16 Very High Very High Very High
Acute Myocarditis 58 96.74 Very High Very High Very High
Thrombosis 1 93.80 High High
Cancer 41 92.84 High High
Pressure And Volume Under Development 4 91.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Development of muscle soreness and tenderness, and increases in plasma CK activity were significantly (P < 0.05) smaller after the second than the first bout.
Positive_regulation (increases) of CK in plasma associated with myalgia
1) Confidence 0.69 Published 2010 Journal Eur. J. Appl. Physiol. Section Abstract Doc Link 19908060 Disease Relevance 0.25 Pain Relevance 0.07
Increases in serum CK activity and muscle soreness were also significantly (P < 0.05) greater for the stimulation than voluntary exercise.
Positive_regulation (Increases) of CK in muscle associated with myalgia
2) Confidence 0.54 Published 2008 Journal J. Appl. Physiol. Section Abstract Doc Link 17975128 Disease Relevance 0.18 Pain Relevance 0
Venom induced a rapid increment in serum creatine kinase (CK) levels, concomitant with a reduction in gastrocnemius muscle CK activity, whereas no increments in muscle lactic acid were detected.
Positive_regulation (increment) of CK in gastrocnemius
3) Confidence 0.41 Published 2001 Journal Int J Exp Pathol Section Abstract Doc Link 11422541 Disease Relevance 0.85 Pain Relevance 0.12
Using tissue microarray technology, 1,059 lymphoma and acute leukemia cases, covering the most common disease entities, were tested for aberrant CK expression using CK22.
Positive_regulation (using) of CK22 in covering associated with leukemia, lymphatic system cancer and disease
4) Confidence 0.04 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 1.49 Pain Relevance 0
The diagnosis of acute viral myocarditis was defined as the clinical evidence of acute myocardial dysfunction by physical exam, chest X-ray, electrocardiogram (ECG) and echocardiogram associated with an elevation of cardiac enzymes such as MB isoform of creatine kinase (CK-MB), cardiac troponin T, troponin I and N-terminal fragment of B-type natriuretic peptide (NT-proBNP).
Positive_regulation (elevation) of CK in chest associated with natriuresis, coronary heart disease and acute myocarditis
5) Confidence 0.03 Published 2010 Journal Korean Journal of Pediatrics Section Body Doc Link PMC3004486 Disease Relevance 1.01 Pain Relevance 0

General Comments

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