INT96641

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Context Info
Confidence 0.60
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0.84
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Gad1) lyase activity (Gad1) intracellular (Gad1)
cytoplasm (Gad1)
Anatomy Link Frequency
brain 1
Gad1 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 2 98.66 Very High Very High Very High
substance P 1 98.36 Very High Very High Very High
medulla 2 96.56 Very High Very High Very High
Hippocampus 15 95.28 Very High Very High Very High
cerebral cortex 2 94.64 High High
Glutamate receptor 27 92.24 High High
Dopamine 3 87.84 High High
Glutamate 5 87.48 High High
Pyramidal cell 90 81.12 Quite High
dopamine receptor 1 76.00 Quite High
Disease Link Frequency Relevance Heat
Aggression 8 97.90 Very High Very High Very High
Convulsion 60 95.52 Very High Very High Very High
Aids-related Complex 1 89.72 High High
Infection 10 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Generalized Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
0.08), while the level of GAD67 mRNA was slightly but significantly reduced in the mutant mice (P<0.001).
Transcription (level) of GAD67
1) Confidence 0.60 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615205 Disease Relevance 0.10 Pain Relevance 0.42
1 mRNA were co-localized with those of the GAD67 mRNA, suggesting that expression of the GluR?
Transcription (those) of GAD67
2) Confidence 0.60 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615205 Disease Relevance 0 Pain Relevance 0.23
In SI male mice, aggression can be prevented by treatment with L-methionine (MET), which has also been shown to decrease reelin and GAD67 mRNA expression and maintain normal brain Allo content.
Transcription (expression) of GAD67 in brain associated with aggression
3) Confidence 0.52 Published 2004 Journal Crit Rev Neurobiol Section Abstract Doc Link 15581402 Disease Relevance 0.66 Pain Relevance 0.07
Striatal expression of substance P and enkephalin mRNAs was reduced by about 50% and 30%, respectively, whereas the expression of GAD67 and GAD65 mRNAs was slightly increased and unaltered, respectively.
Transcription (expression) of GAD67 associated with enkephalin and substance p
4) Confidence 0.48 Published 2001 Journal J. Neurochem. Section Abstract Doc Link 11432985 Disease Relevance 0.09 Pain Relevance 0.65

General Comments

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