INT96642

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Context Info
Confidence 0.59
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.88
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Gad2) Golgi apparatus (Gad2) plasma membrane (Gad2)
cytoplasm (Gad2)
Anatomy Link Frequency
brain 2
Gad2 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 2 98.66 Very High Very High Very High
substance P 1 98.36 Very High Very High Very High
Hippocampus 8 95.28 Very High Very High Very High
Glutamate receptor 14 95.04 Very High Very High Very High
cerebral cortex 6 94.64 High High
Dopamine 3 88.64 High High
Glutamate 38 87.48 High High
gABA 60 78.96 Quite High
Pyramidal cell 45 77.76 Quite High
dopamine receptor 1 76.80 Quite High
Disease Link Frequency Relevance Heat
Convulsion 36 98.32 Very High Very High Very High
Generalized Anxiety Disorder 36 95.00 High High
Aids-related Complex 1 89.72 High High
Movement Disorders 4 82.44 Quite High
Cerebral Palsy 86 50.00 Quite Low
Syndrome 28 50.00 Quite Low
Heart Rate Under Development 10 48.24 Quite Low
Milium 4 46.44 Quite Low
Spasticity 40 5.00 Very Low Very Low Very Low
Epilepsy 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was no significant difference in the GAD65 mRNA (P?
Neg (no) Transcription (was) of GAD65
1) Confidence 0.59 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2615205 Disease Relevance 0.10 Pain Relevance 0.43
GAD2, located at 10p13-p11.2, is transcribed to produce a 5.6 kb mRNA in islets and brain, encoding a 65 kDa protein (585 AA residues).
Transcription (transcribed) of GAD2 in brain
2) Confidence 0.57 Published 2004 Journal BMC Neurol Section Body Doc Link PMC544830 Disease Relevance 0.34 Pain Relevance 0.26
GAD2, located at 10p13-p11.2, is transcribed to produce a 5.6 kb mRNA in islets and brain, encoding a 65 kDa protein (585 AA residues).
Transcription (produce) of GAD2 in brain
3) Confidence 0.57 Published 2004 Journal BMC Neurol Section Body Doc Link PMC544830 Disease Relevance 0.34 Pain Relevance 0.26
Striatal expression of substance P and enkephalin mRNAs was reduced by about 50% and 30%, respectively, whereas the expression of GAD67 and GAD65 mRNAs was slightly increased and unaltered, respectively.
Transcription (expression) of GAD65 associated with enkephalin and substance p
4) Confidence 0.52 Published 2001 Journal J. Neurochem. Section Abstract Doc Link 11432985 Disease Relevance 0.09 Pain Relevance 0.65

General Comments

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