INT96704

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Context Info
Confidence 0.37
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ntf3) cytoplasmic membrane-bounded vesicle (Ntf3)
Anatomy Link Frequency
ciliary 2
Ntf3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
neurotrophin 3 8 100.00 Very High Very High Very High
Somatostatin 7 100.00 Very High Very High Very High
Nerve growth factor 3 98.60 Very High Very High Very High
tetrodotoxin 1 52.48 Quite High
nMDA receptor 2 25.00 Low Low
Sciatica 2 25.00 Low Low
Glutamate 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, receptors for ciliary neurotrophic factor and pleiotrophin were downregulated after avulsion.
Negative_regulation (downregulated) of Positive_regulation (ciliary) of neurotrophic factor in ciliary
1) Confidence 0.37 Published 2009 Journal J. Neuropathol. Exp. Neurol. Section Abstract Doc Link 19104442 Disease Relevance 0 Pain Relevance 0
BDNF or NT-3 induction of somatostatin release was inhibited by the Trk inhibitors K-252a and genistein, whereas K-252b, a less effective inhibitor, had no effect.
Negative_regulation (inhibited) of Positive_regulation (induction) of NT-3 associated with neurotrophin 3 and somatostatin
2) Confidence 0.10 Published 2001 Journal Neuroendocrinology Section Abstract Doc Link 11435757 Disease Relevance 0 Pain Relevance 0.68

General Comments

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