INT96708

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Context Info
Confidence 0.01
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf, SST) extracellular space (SST) cytoplasmic membrane-bounded vesicle (Bdnf)
cell-cell signaling (SST)
Bdnf (Rattus norvegicus)
SST (Homo sapiens)
Pain Link Frequency Relevance Heat
neurotrophin 3 16 100.00 Very High Very High Very High
Somatostatin 14 100.00 Very High Very High Very High
Nerve growth factor 6 99.68 Very High Very High Very High
tetrodotoxin 2 51.36 Quite High
nMDA receptor 4 25.00 Low Low
Glutamate 2 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We demonstrated that BDNF, and to a lesser extent NT-3, induced significant time- and concentration-dependent somatostatin release, while NGF was devoid of any effect.
BDNF Positive_regulation (induced) of Localization (release) of somatostatin associated with nerve growth factor, neurotrophin 3 and somatostatin
1) Confidence 0.01 Published 2001 Journal Neuroendocrinology Section Abstract Doc Link 11435757 Disease Relevance 0 Pain Relevance 0.63
BDNF or NT-3 induction of somatostatin release was inhibited by the Trk inhibitors K-252a and genistein, whereas K-252b, a less effective inhibitor, had no effect.
BDNF Positive_regulation (induction) of Localization (release) of somatostatin associated with neurotrophin 3 and somatostatin
2) Confidence 0.01 Published 2001 Journal Neuroendocrinology Section Abstract Doc Link 11435757 Disease Relevance 0 Pain Relevance 0.68

General Comments

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