INT96795

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Context Info
Confidence 0.49
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ITIH4, OPRM1) extracellular region (ITIH4) Golgi apparatus (OPRM1)
endoplasmic reticulum (OPRM1) signal transducer activity (OPRM1) cytoplasm (ITIH4)
Anatomy Link Frequency
internal thoracic artery 2
ITIH4 (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
mu opioid receptor 3 100.00 Very High Very High Very High
cytokine 1 100.00 Very High Very High Very High
Morphine 4 98.80 Very High Very High Very High
antagonist 1 88.00 High High
narcan 1 86.56 High High
opiate 1 83.76 Quite High
Opioid receptor 1 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 97.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We find that chronic exposure of human saphenous vein, atria and internal thoracic artery endothelium to the human immunodeficiency virus surface glycoprotein gp120, results in an increase in endothelial mu opioid receptor expression (52%). gp120 acts, in this regard, as a proinflammatory cytokine (e.g. interleukin-1-alpha) by increasing endothelial mu opioid receptor expression.
gp120 Positive_regulation (increasing) of Gene_expression (expression) of mu opioid receptor in internal thoracic artery associated with acquired immune deficiency syndrome or hiv infection, mu opioid receptor and cytokine
1) Confidence 0.49 Published 2001 Journal Int. J. Mol. Med. Section Abstract Doc Link 11445868 Disease Relevance 0.17 Pain Relevance 0.76

General Comments

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