INT96796

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Context Info
Confidence 0.20
First Reported 2001
Last Reported 2006
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 1.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ITIH4, OPRM1) extracellular region (ITIH4) Golgi apparatus (OPRM1)
endoplasmic reticulum (OPRM1) signal transducer activity (OPRM1) cytoplasm (ITIH4)
Anatomy Link Frequency
macrophage 2
vascular endothelium 2
ITIH4 (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
mu opioid receptor 12 100.00 Very High Very High Very High
Morphine 5 100.00 Very High Very High Very High
Opioid receptor 1 1 100.00 Very High Very High Very High
cytokine 2 95.28 Very High Very High Very High
Inflammation 1 94.88 High High
Opioid 2 85.32 High High
antagonist 1 77.48 Quite High
narcan 2 76.76 Quite High
opiate 1 75.36 Quite High
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 7 100.00 Very High Very High Very High
Leukemia 1 98.80 Very High Very High Very High
INFLAMMATION 1 94.88 High High
Infection 1 79.76 Quite High
Opiate Addiction 1 76.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HIV gp120 and morphine alter mu opiate receptor expression in human vascular endothelium.
gp120 Regulation (alter) of Gene_expression (expression) of opiate receptor in vascular endothelium associated with acquired immune deficiency syndrome or hiv infection, opioid receptor 1 and morphine
1) Confidence 0.20 Published 2001 Journal Int. J. Mol. Med. Section Title Doc Link 11445868 Disease Relevance 0.19 Pain Relevance 0.74
In this study, we examined the effects of HIV-1 gp120 on MOR expression in HL-60 human promyelocytic leukemia cells differentiated into macrophage-like cells by TPA.
gp120 Spec (examined) Regulation (effects) of Gene_expression (expression) of MOR in macrophage associated with leukemia, acquired immune deficiency syndrome or hiv infection and mu opioid receptor
2) Confidence 0.20 Published 2006 Journal Int. Immunopharmacol. Section Abstract Doc Link 16846840 Disease Relevance 0.69 Pain Relevance 0.66

General Comments

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