INT96835

Context Info Confidence 0.03 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.69 Pain Relevance 0.39

cytosol (WAS) plasma membrane (Cnr2) protein complex assembly (WAS) signal transducer activity (Cnr2) cytoplasm (WAS)

WAS (Homo sapiens) Cnr2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Cannabinoid receptor 2 100.00 Cannabinoid 7 98.32 Pain 1 96.68 agonist 2 84.24 Endocannabinoid 3 75.00 Antiemetics 1 25.00 Analgesic 1 25.00

Disease Link Frequency Relevance Heat Wasting Syndrome 1 99.56 Muscular Spasm 1 98.68 Vomiting 2 98.08 Glaucoma 1 97.44 Anxiety Disorder 1 97.04 Pain 1 96.68

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Delta(9)-THC binds to and activates two known cannabinoid receptors found in mammalian tissue, CB1 and CB2.

THC Positive_regulation (activates) of CB2 associated with cannabinoid receptor

1) Confidence 0.03 Published 2001 Journal Pharmacol. Ther. Section Abstract Doc Link 11448725 Disease Relevance 0.69 Pain Relevance 0.39

General Comments

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