INT96860

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Context Info
Confidence 0.33
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.40
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ang) extracellular space (Ang) extracellular region (Ang)
RNA binding (Ang) nucleus (Ang) nuclease activity (Ang)
Anatomy Link Frequency
podocytes 2
Ang (Mus musculus)
Pain Link Frequency Relevance Heat
member 8 1 93.92 High High
Calcium channel 2 89.20 High High
fibrosis 2 88.76 High High
Inflammation 3 53.28 Quite High
Angina 2 50.00 Quite Low
chemokine 1 20.96 Low Low
Bioavailability 1 15.16 Low Low
antagonist 5 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 9 100.00 Very High Very High Very High
Renal Disease 23 99.92 Very High Very High Very High
Fibrosis 3 88.76 High High
Chronic Renal Failure 64 82.08 Quite High
Diabetes Mellitus 28 79.60 Quite High
Disease 8 78.92 Quite High
Cv General 3 Under Development 2 65.00 Quite High
Cv Unclassified Under Development 18 57.20 Quite High
Vasculitis 1 53.28 Quite High
Stress 1 52.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although more research is needed, activation of the (pro)renin receptor may contribute to the pathology of renal disease by increasing local Ang II formation and by increasing the expression of profibrotic mediators.
Positive_regulation (increasing) of Ang Binding (formation) of associated with renal disease
1) Confidence 0.33 Published 2010 Journal Cardiovasc Drugs Ther Section Body Doc Link PMC2887501 Disease Relevance 0.85 Pain Relevance 0.07
Angiotensin II (Ang II) has been recognized as an apoptosis inducer in podocytes, but the mechanism of apoptosis induced by Ang II is unclear.
Positive_regulation (inducer) of Ang Binding (recognized) of in podocytes associated with apoptosis
2) Confidence 0.32 Published 2009 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 19546355 Disease Relevance 0.49 Pain Relevance 0.14
RESULTS: Cardiac Ang II generation was higher in patients with UA than it was in patients with SA or in controls (p < 0.001) due to increased de novo cardiac Ang I formation and its enhanced fractional conversion rate to Ang II.
Positive_regulation (increased) of Ang Binding (formation) of
3) Confidence 0.03 Published 2001 Journal J. Am. Coll. Cardiol. Section Body Doc Link 11451295 Disease Relevance 0.07 Pain Relevance 0

General Comments

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