INT96884

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Context Info
Confidence 0.60
First Reported 2001
Last Reported 2004
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.54
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CYP1A1) mitochondrion (CYP1A1) small molecule metabolic process (CYP1A1)
oxidoreductase activity (CYP1A1) endoplasmic reticulum (CYP1A1) enzyme binding (CYP1A1)
Anatomy Link Frequency
endometrium 2
CYP1A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 4 98.28 Very High Very High Very High
pain pelvic 1 73.92 Quite High
aspirin 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis (extended) 4 98.28 Very High Very High Very High
Disease 3 97.00 Very High Very High Very High
Reprotox - General 3 1 73.92 Quite High
Colon Cancer 40 69.44 Quite High
Apoptosis 11 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Leukemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium.
Regulation (Effect) of Gene_expression (expression) of CYP1A1 in endometrium
1) Confidence 0.60 Published 2001 Journal Toxicol. Sci. Section Title Doc Link 11452143 Disease Relevance 0.42 Pain Relevance 0.20
CYP1A1 expression did not change in HT29 cells in response to curcumin, however CYP1B1 expression was downregulated by the high concentration of curcumin (Table 2).
Neg (not) Regulation (change) of Gene_expression (expression) of CYP1A1
2) Confidence 0.10 Published 2004 Journal J Carcinog Section Body Doc Link PMC421747 Disease Relevance 0.12 Pain Relevance 0

General Comments

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