INT96885

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Context Info
Confidence 0.80
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.11
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP1B1) endoplasmic reticulum (CYP1B1)
Anatomy Link Frequency
glands 1
CYP1B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 8 78.12 Quite High
endometriosis 4 73.84 Quite High
pain pelvic 1 59.20 Quite High
halothane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glaucoma 290 99.86 Very High Very High Very High
Photophobia 3 88.92 High High
Lacrimal Apparatus Diseases 1 88.28 High High
Congenital Anomalies 4 87.60 High High
Ocular Hypertension 38 81.16 Quite High
Endometriosis (extended) 4 73.84 Quite High
Disease 38 66.16 Quite High
Reprotox - General 3 1 59.20 Quite High
Nervous System Injury 2 26.00 Quite Low
Brain Stem Infarctions 1 15.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In explants cultured with and without TCDD exposure, CYP1B1 protein was localized in the cytoplasm of the new surface epithelial membrane and glands closest to the surface.
Localization (localized) of CYP1B1 protein in glands
1) Confidence 0.80 Published 2001 Journal Toxicol. Sci. Section Abstract Doc Link 11452143 Disease Relevance 0.32 Pain Relevance 0.16
CYP1B1 encodes a member of the cytochrome P450 superfamily, subfamily I, and is composed of three exons with the translated region beginning at the 5?
Localization (composed) of CYP1B1
2) Confidence 0.75 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2645906 Disease Relevance 0.94 Pain Relevance 0
The highest allelic frequency among PCG index cases with CYP1B1 mutations corresponded to mutations T404fsX30 (23.0%) and R355fsX69 (11.5%; Table 2).
Localization (cases) of CYP1B1 associated with glaucoma
3) Confidence 0.75 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2645906 Disease Relevance 0.31 Pain Relevance 0
CYP1B1 and MYOC mutation screening
Localization (screening) of CYP1B1
4) Confidence 0.74 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2901188 Disease Relevance 0.54 Pain Relevance 0.08

General Comments

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