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Context Info
Confidence 0.02
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CYP3A4, HAGH) mitochondrion (HAGH) small molecule metabolic process (CYP3A4)
endoplasmic reticulum (CYP3A4) carbohydrate metabolic process (HAGH) enzyme binding (CYP3A4)
Anatomy Link Frequency
liver 1
CYP3A4 (Homo sapiens)
HAGH (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 1 84.96 Quite High
Paracetamol 1 70.24 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The specificity of inhibition by 8-phenyltheophylline was assessed by measuring its effect on debrisoquine 4-hydroxylase (CYP2D6), terfenadine hydroxylase (CYP3A4), chlorzoxazone 6-hydroxylase (CYP2E1) and tolbutamide 4-hydroxylase (CYP2C9) activities in human liver microsomal fraction.
CYP3A4 Regulation (effect) of terfenadine hydroxylase in liver
1) Confidence 0.02 Published 2001 Journal Xenobiotica Section Abstract Doc Link 11465391 Disease Relevance 0 Pain Relevance 0.11

General Comments

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