INT97098

Context Info Confidence 0.45 First Reported 2001 Last Reported 2001 Negated 0 Speculated 1 Reported most in Title Documents 3 Total Number 3 Disease Relevance 0.97 Pain Relevance 1.30

plasma membrane (Dlg4) protein complex assembly (Dlg4) response to stress (Dlg4) cytoplasm (Dlg4)

Anatomy Link Frequency spinal 4 nerve 2 Dlg4 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Lasting pain 1 99.26 Neuropathic pain 3 98.76 isoflurane 4 97.88 Thermal hyperalgesia 5 96.40 nMDA receptor 3 95.20 intrathecal 1 82.88 anesthesia 2 73.20 Brush evoked pain 1 68.32 neuralgia 3 25.00

Disease Link Frequency Relevance Heat Nervous System Injury 2 99.60 Pain 1 99.26 Neuropathic Pain 4 98.76 Hyperalgesia 5 96.40 Nociception 2 91.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To address the role of PSD-95/SAP90 in chronic pain, the present study investigated the effect of the deficiency of PSD-95/SAP90 on nerve injury-induced neuropathic pain.

Spec (investigated) Regulation (effect) of Spec (investigated) Negative_regulation (deficiency) of PSD-95 in nerve associated with nervous system injury, lasting pain and neuropathic pain

1) Confidence 0.45 Published 2001 Journal Neuroreport Section Abstract Doc Link 11711866 Disease Relevance 0.79 Pain Relevance 0.74

Effect of the deficiency of spinal PSD-95/SAP90 on the minimum alveolar anesthetic concentration of isoflurane in rats.

Regulation (Effect) of Negative_regulation (deficiency) of SAP90 in spinal associated with isoflurane

2) Confidence 0.45 Published 2001 Journal Anesthesiology Section Title Doc Link 11465592 Disease Relevance 0.09 Pain Relevance 0.28

Effect of the deficiency of spinal PSD-95/SAP90 on the minimum alveolar anesthetic concentration of isoflurane in rats.

Regulation (Effect) of Negative_regulation (deficiency) of PSD-95 in spinal associated with isoflurane

3) Confidence 0.45 Published 2001 Journal Anesthesiology Section Title Doc Link 11465592 Disease Relevance 0.09 Pain Relevance 0.28

General Comments

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