INT97157

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Context Info
Confidence 0.75
First Reported 2001
Last Reported 2010
Negated 0
Speculated 2
Reported most in Abstract
Documents 7
Total Number 9
Disease Relevance 5.14
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD177)
Anatomy Link Frequency
megakaryocytes 2
NB3 1
adrenal gland 1
platelet 1
CD177 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 96.24 Very High Very High Very High
Inflammation 30 95.88 Very High Very High Very High
bradykinin 2 91.28 High High
Serotonin 3 89.32 High High
Neurotransmitter 1 84.08 Quite High
Snapping jaw 15 82.80 Quite High
medulla 4 78.68 Quite High
Angina 1 72.56 Quite High
Raphe 1 71.84 Quite High
Raphe magnus 1 70.56 Quite High
Disease Link Frequency Relevance Heat
Erythremia 6 100.00 Very High Very High Very High
Sprains And Strains 2 97.70 Very High Very High Very High
Erythrocytosis 2 97.30 Very High Very High Very High
Injury 3 97.04 Very High Very High Very High
Pain 2 96.24 Very High Very High Very High
Adhesions 2 96.00 Very High Very High Very High
INFLAMMATION 30 95.88 Very High Very High Very High
Pseudorabies 1 92.88 High High
Myelodysplastic Syndromes 6 88.40 High High
Myeloproliferative Disorder 6 87.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gene expression data of 51 of the 54 BCs and 4 normal breast (NB) samples (NB1, NB2, NB3 and NB4, representing samples from 4 women and 3 commercial pools of respectively 1, 2 and 4 normal breast RNA, Clontech, Palo Alto, CA) were quantified by using whole-genome DNA microarrays (HG-U133 plus 2.0, Affymetrix).
Gene_expression (expression) of NB1 in NB3
1) Confidence 0.75 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2958950 Disease Relevance 0.06 Pain Relevance 0
It was found that the characterized values of albumin in SF of patients with the disorders were the fraction of HMA (f (HMA), 65.8 +/- 9.1%), the fraction of HNA-1 (f (HNA-1), 31.3 +/- 8.8%), and the fraction of HNA-2 (f (HNA-2), 2.9 +/- 0.9%), respectively, and similarly the values of albumin in serum of same subjects were f (HMA), 79.4 +/- 4.0%; f (HNA-1), 18.7 +/- 3.8%; and f (HNA-2), 1.9 +/- 0.5%.
Gene_expression (fraction) of HNA-1
2) Confidence 0.67 Published 2003 Journal Jpn. J. Physiol. Section Abstract Doc Link 14975181 Disease Relevance 0.21 Pain Relevance 0.21
It was found that the characterized values of albumin in SF of patients with the disorders were the fraction of HMA (f (HMA), 65.8 +/- 9.1%), the fraction of HNA-1 (f (HNA-1), 31.3 +/- 8.8%), and the fraction of HNA-2 (f (HNA-2), 2.9 +/- 0.9%), respectively, and similarly the values of albumin in serum of same subjects were f (HMA), 79.4 +/- 4.0%; f (HNA-1), 18.7 +/- 3.8%; and f (HNA-2), 1.9 +/- 0.5%.
Gene_expression (fraction) of HNA-2
3) Confidence 0.67 Published 2003 Journal Jpn. J. Physiol. Section Abstract Doc Link 14975181 Disease Relevance 0.21 Pain Relevance 0.21
It was found that the characterized values of albumin in SF of patients with the disorders were the fraction of HMA (f (HMA), 65.8 +/- 9.1%), the fraction of HNA-1 (f (HNA-1), 31.3 +/- 8.8%), and the fraction of HNA-2 (f (HNA-2), 2.9 +/- 0.9%), respectively, and similarly the values of albumin in serum of same subjects were f (HMA), 79.4 +/- 4.0%; f (HNA-1), 18.7 +/- 3.8%; and f (HNA-2), 1.9 +/- 0.5%.
Gene_expression (fraction) of HNA-1
4) Confidence 0.67 Published 2003 Journal Jpn. J. Physiol. Section Abstract Doc Link 14975181 Disease Relevance 0.16 Pain Relevance 0.16
Here, we investigated the role of B(1) receptor homo-oligomerization in cell surface receptor expression.
Gene_expression (expression) of cell surface receptor
5) Confidence 0.33 Published 2005 Journal Mol. Pharmacol. Section Abstract Doc Link 15492119 Disease Relevance 0.29 Pain Relevance 0.23
Polycythemia vera is distinguished from reactive erythrocytosis through erythropoietin independent growth of erythroid progenitors in vitro, suppressed levels of endogenous erythropoietin, possible overexpression of PRV-1 (polycythemia rubra vera-1), decreased c-Mpl expression on megakaryocytes, as well as overexpression of bcl-xL, and potentially aberrant activity of the Jak-Stat pathway.
Spec (possible) Gene_expression (overexpression) of PRV-1 in megakaryocytes associated with erythremia and erythrocytosis
6) Confidence 0.21 Published 2002 Journal Int. J. Hematol. Section Abstract Doc Link 12430925 Disease Relevance 1.60 Pain Relevance 0.03
Polycythemia vera is distinguished from reactive erythrocytosis through erythropoietin independent growth of erythroid progenitors in vitro, suppressed levels of endogenous erythropoietin, possible overexpression of PRV-1 (polycythemia rubra vera-1), decreased c-Mpl expression on megakaryocytes, as well as overexpression of bcl-xL, and potentially aberrant activity of the Jak-Stat pathway.
Spec (possible) Gene_expression (overexpression) of polycythemia rubra vera-1 in megakaryocytes associated with erythremia and erythrocytosis
7) Confidence 0.18 Published 2002 Journal Int. J. Hematol. Section Abstract Doc Link 12430925 Disease Relevance 1.72 Pain Relevance 0.03
The linked C807T/G873A polymorphisms in the GP Ia gene are correlated with a variable expression of the platelet surface receptor, the 807 TT/873 AA genotype being associated with a higher receptor density.
Gene_expression (expression) of surface receptor in platelet
8) Confidence 0.02 Published 2001 Journal Br. J. Haematol. Section Abstract Doc Link 11472360 Disease Relevance 0.55 Pain Relevance 0.07
PRV-152, a strain that expresses enhanced green fluorescent protein, was injected into sympathectomized gastrocnemius muscle, while PRV-BaBlu, which expresses beta-galactosidase, was injected into the adrenal gland in the same animals.
Gene_expression (expresses) of PRV-BaBlu in adrenal gland associated with sprains and strains
9) Confidence 0.00 Published 2006 Journal J. Comp. Neurol. Section Abstract Doc Link 17072838 Disease Relevance 0.34 Pain Relevance 0.41

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