INT97171

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Context Info
Confidence 0.43
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 4.25
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Ear1) cellular_component (Ear1) biological_process (Ear1)
nuclease activity (Ear1)
Anatomy Link Frequency
eosinophil 3
granulocytes 2
blood 2
Ear1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 19 98.28 Very High Very High Very High
Inflammation 38 98.12 Very High Very High Very High
Antihistamine 22 82.28 Quite High
Inflammatory mediators 2 69.00 Quite High
Morphine 1 32.56 Quite Low
abdominal pain 4 25.00 Low Low
addiction 1 25.00 Low Low
fibrosis 8 5.00 Very Low Very Low Very Low
Onset of action 7 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilia 1 100.00 Very High Very High Very High
Anaphylaxis 3 98.96 Very High Very High Very High
INFLAMMATION 41 98.12 Very High Very High Very High
Disease 13 97.60 Very High Very High Very High
Overdose 2 97.48 Very High Very High Very High
Necrosis 1 97.12 Very High Very High Very High
Cancer 1 96.76 Very High Very High Very High
Nasal Polyps 1 92.92 High High
Airway Remodeling 26 87.12 High High
Wheal 4 76.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among proteins secreted from activated eosinophil granulocytes, eosinophil cationic protein (ECP) is the most useful tool for the follow-up of inflammatory diseases.
Localization (secreted) of ECP in eosinophil associated with inflammation and disease
1) Confidence 0.43 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.63 Pain Relevance 0.05
Among proteins secreted from activated eosinophil granulocytes, eosinophil cationic protein (ECP) is the most useful tool for the follow-up of inflammatory diseases.
Localization (secreted) of eosinophil cationic protein in eosinophil associated with inflammation and disease
2) Confidence 0.43 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.63 Pain Relevance 0.05
One possible explanation is that the increased numbers of eosinophils in the airway in Siglec-F deficient mice express increased levels of mediators that can influence mucus secretion including granule mediators (ECP, MBP)[29,30], lipid mediators (LTC4)[31], cytokines (IL-13)[31], or other at present unknown mediators.
Localization (secretion) of ECP in eosinophils associated with cytokine
3) Confidence 0.21 Published 2010 Journal Respir Res Section Body Doc Link PMC2988013 Disease Relevance 0.40 Pain Relevance 0.05
Among proteins secreted from activated eosinophil granulocytes, eosinophil cationic protein (ECP) is the most useful tool for the follow-up of inflammatory diseases.
Localization (secreted) of eosinophil cationic protein in granulocytes associated with inflammation and disease
4) Confidence 0.15 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.63 Pain Relevance 0.05
Among proteins secreted from activated eosinophil granulocytes, eosinophil cationic protein (ECP) is the most useful tool for the follow-up of inflammatory diseases.
Localization (secreted) of ECP in granulocytes associated with inflammation and disease
5) Confidence 0.15 Published 2009 Journal Mikrobiyol Bul Section Abstract Doc Link 19621614 Disease Relevance 0.63 Pain Relevance 0.05
In the present study we measured tryptase and eosinophil cationic protein in post-mortem blood of 48 deaths after heroin injection.
Localization (measured) of eosinophil cationic protein in blood
6) Confidence 0.13 Published 2001 Journal Forensic Sci. Int. Section Abstract Doc Link 11473801 Disease Relevance 0.47 Pain Relevance 0
Ebastine also reduces the release of GM-CSF in nasal secretions, nasal eosinophilia (assessed using nasal smears), serum eosinophil cationic protein levels, and peripheral blood eosinophil count.
Localization (secretions) of serum eosinophil cationic protein in blood associated with eosinophilia
7) Confidence 0.01 Published 2010 Journal Patient Prefer Adherence Section Body Doc Link PMC3003605 Disease Relevance 0.86 Pain Relevance 0.19

General Comments

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