INT97189

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.73
First Reported 2001
Last Reported 2010
Negated 2
Speculated 1
Reported most in Abstract
Documents 10
Total Number 10
Disease Relevance 7.70
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd33) plasma membrane (Cd33)
Anatomy Link Frequency
hematopoietic stem cells 3
bone marrow 1
blast cells 1
Cd33 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 4 90.80 High High
Pain 4 81.68 Quite High
cytokine 10 66.00 Quite High
Potency 3 47.36 Quite Low
palliative 16 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 107 100.00 Very High Very High Very High
Leukemia 26 100.00 Very High Very High Very High
Acute Myeloid Leukemia 90 99.20 Very High Very High Very High
Leukocytosis 4 99.04 Very High Very High Very High
Chronic Myelomonocytic Leukemia 4 99.00 Very High Very High Very High
Recurrence 36 98.40 Very High Very High Very High
Death 10 97.20 Very High Very High Very High
Toxicity 42 96.56 Very High Very High Very High
Myocardial Infarction 8 96.56 Very High Very High Very High
Pleural Effusion 5 95.64 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The antigen CD33 is expressed on blast cells in 80% to 90% of acute myeloid leukemia (AML) cases but, importantly, is not expressed on pluripotent hematopoietic stem cells or on nonhematologic cells.
Neg (not) Gene_expression (expressed) of CD33 in hematopoietic stem cells associated with leukemia and myeloid leukemia
1) Confidence 0.73 Published 2001 Journal Semin. Hematol. Section Abstract Doc Link 11474494 Disease Relevance 0.40 Pain Relevance 0
The antigen CD33 is expressed on blast cells in 80% to 90% of acute myeloid leukemia (AML) cases but, importantly, is not expressed on pluripotent hematopoietic stem cells or on nonhematologic cells.
Gene_expression (expressed) of CD33 in hematopoietic stem cells associated with leukemia and myeloid leukemia
2) Confidence 0.73 Published 2001 Journal Semin. Hematol. Section Abstract Doc Link 11474494 Disease Relevance 0.38 Pain Relevance 0
The surface molecule CD33 is expressed on leukemic blasts of most patients with AML [11].
Gene_expression (expressed) of CD33 associated with myeloid leukemia
3) Confidence 0.57 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2902223 Disease Relevance 1.21 Pain Relevance 0
Cells were analyzed for the expression of surface markers like Annexin V, CD34, CD38, Bcl-2, CD33, CD19 and CD3 (BD pharmingen- San Jose, California).
Spec (analyzed) Gene_expression (expression) of CD33
4) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923186 Disease Relevance 0.18 Pain Relevance 0.03
His diagnosis was then changed to CMML-2 and pleural infiltration due to leukemic cells expressing CD13, CD14 and CD33.
Gene_expression (expressing) of CD33 associated with chronic myelomonocytic leukemia
5) Confidence 0.37 Published 2005 Journal Rinsho Ketsueki Section Abstract Doc Link 16447718 Disease Relevance 1.38 Pain Relevance 0.09
Approximately 80% to 90% of pediatric AML patients have myeloid blast cells that express the CD33 surface antigen [10].
Gene_expression (express) of CD33 in blast cells associated with acute myeloid leukemia
6) Confidence 0.22 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1523361 Disease Relevance 0.55 Pain Relevance 0
In responders, it was probably related to expression of the CD33 target by normal bone marrow progenitors.
Gene_expression (expression) of CD33 in bone marrow
7) Confidence 0.22 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1523361 Disease Relevance 1.24 Pain Relevance 0
CD33 expression exceeded 20% in all cases.


Gene_expression (expression) of CD33
8) Confidence 0.17 Published 2006 Journal BMC Cancer Section Abstract Doc Link PMC1523361 Disease Relevance 0.96 Pain Relevance 0
Both the number of CD34+ cells coexpressing CD33, CD38, or CD117 and the number of HPCs was higher (P < .02 for all) in patients with AMI at T0 than in CTRLs, as was the number of hematopoietic colonies (P < .03).
Gene_expression (coexpressing) of CD33 in HPCs associated with myocardial infarction
9) Confidence 0.10 Published 2005 Journal Blood Section Abstract Doc Link 15345590 Disease Relevance 0.82 Pain Relevance 0.24
Staining for CD2, CD3, CD5, CD7, CD20, CD23, CD33, CD14, CD15, AC133 and KOR-SA3544 was negative.
Neg (negative) Gene_expression (negative) of CD33
10) Confidence 0.08 Published 2003 Journal J. Exp. Clin. Cancer Res. Section Abstract Doc Link 15053308 Disease Relevance 0.57 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox