INT97261

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Context Info
Confidence 0.26
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
cell-cell signaling (IL2)
Anatomy Link Frequency
T-cell 2
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 11 100.00 Very High Very High Very High
abatacept 9 100.00 Very High Very High Very High
palliative 1 66.44 Quite High
Inflammation 2 63.44 Quite High
Disease Link Frequency Relevance Heat
Syndrome 11 99.20 Very High Very High Very High
Rheumatoid Arthritis 1 80.12 Quite High
Salivary Gland Disease 1 64.84 Quite High
Frailty 1 63.92 Quite High
INFLAMMATION 2 63.44 Quite High
Autoimmune Disease 2 58.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to the effect of abatacept on proliferation, T-cell cytokines, IL-2, TNFalpha and IFNgamma were also reduced.
Negative_regulation (reduced) of Regulation (effect) of IL-2 in T-cell associated with abatacept and cytokine
1) Confidence 0.26 Published 2008 Journal Clin. Immunol. Section Abstract Doc Link 17945538 Disease Relevance 0.08 Pain Relevance 0.92
In addition, the study assessed salivary IL-6, IFN, and IL-2 concentrations among 18 Sjögren's syndrome patients before and after administration of IFN via the oral mucosal route.
Negative_regulation (assessed) of Regulation (concentrations) of IL-2 associated with syndrome
2) Confidence 0.08 Published 2001 Journal Clin Oral Investig Section Abstract Doc Link 11480812 Disease Relevance 0.96 Pain Relevance 0.25

General Comments

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