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Context Info
Confidence 0.06
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL1A, Timp1) cell proliferation (IL1A) cytosol (IL1A)
extracellular space (IL1A) aging (Timp1) proteinaceous extracellular matrix (Timp1)
Anatomy Link Frequency
PGE2 2
IL1A (Homo sapiens)
Timp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 3 93.08 High High
pulpitis 1 92.84 High High
metalloproteinase 4 75.00 Quite High
Inflammation 1 53.72 Quite High
Disease Link Frequency Relevance Heat
Pulpitis 1 92.84 High High
Cancer 2 75.00 Quite High
Necrosis 2 75.00 Quite High
Disease 1 54.08 Quite High
INFLAMMATION 1 53.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The differential regulation of IL-1alpha or TNF-alpha-induced MMP-1 and TIMP-1 mRNA synthesis, as well as the direct upregulation of TIMP-1 gene expression by PGE2, also implied that prostaglandin may serve as a protective mechanism from excessive tissue breakdown during pulpitis.
IL-1alpha Positive_regulation (induced) of Transcription (synthesis) of TIMP-1 in PGE2 associated with pulpitis
1) Confidence 0.06 Published 2001 Journal J Endod Section Abstract Doc Link 11487149 Disease Relevance 0.47 Pain Relevance 0.34

General Comments

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