INT97446

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Context Info
Confidence 0.46
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 3.74
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Mki67) nucleolus (Mki67) nucleus (Mki67)
intracellular (Mki67) cytoplasm (Mki67)
Anatomy Link Frequency
neuron 1
bladder 1
Mki67 (Mus musculus)
Pain Link Frequency Relevance Heat
COX2 78 94.80 High High
palliative 2 72.84 Quite High
Hippocampus 2 70.44 Quite High
ischemia 23 66.12 Quite High
Inflammation 13 60.64 Quite High
pain flank 1 58.96 Quite High
cINOD 4 50.00 Quite Low
imagery 54 28.92 Quite Low
cva 2 21.24 Low Low
cytokine 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 280 99.56 Very High Very High Very High
Pseudomyxoma Peritonei 44 98.40 Very High Very High Very High
Bladder Cancer 32 94.56 High High
Colon Cancer 5 93.04 High High
Breast Cancer 34 83.68 Quite High
Recurrence 18 81.72 Quite High
Disease 43 77.12 Quite High
Overactive Bladder 2 77.04 Quite High
Adenocarcinoma 5 75.00 Quite High
Intestinal Cancer 1 70.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nuclear presence of the proliferation marker pKi67 was detected in 10–50% of cells in the PMP-1 primary tumor and main surgical specimen, and this feature was conserved throughout the animal passages.
Localization (presence) of pKi67 associated with pseudomyxoma peritonei and cancer
1) Confidence 0.46 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1920528 Disease Relevance 1.22 Pain Relevance 0
Quantitatively, fractions of nestin-EGFP+ cells colocalizing with Ki67 and the specific markers MAP-2, GFAP, and Neu-N were ?
Localization (colocalizing) of Ki67
2) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852409 Disease Relevance 0.13 Pain Relevance 0.07
In other published studies using non-anthracycline based chemoendocrine agents [11], it was reported that positive ER, absence of c-erbB2 and decrease in Ki-67 were associated with a good clinical response.
Localization (decrease) of Ki-67
3) Confidence 0.28 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2217558 Disease Relevance 0.34 Pain Relevance 0.07
METHODS AND RESULTS: We assessed the distribution of five cytokeratins (CK) (CK7, 8, 18, 19 and 20) and Ki67 for the ability to distinguish NSAID from H. pylori gastropathies.
Localization (distribution) of Ki67
4) Confidence 0.27 Published 2001 Journal Histopathology Section Body Doc Link 11493329 Disease Relevance 0 Pain Relevance 0
Our analysis indicates an increased lymphatic density during cancer progression and a co-localization of Ki-67 with some of LYVE-1-positive lymphatics, suggesting cancer-induced lymphangiogenesis (Figure 4), as it was recently suggested in human bladder cancer [10,37].
Localization (localization) of Ki-67 in bladder associated with cancer and bladder cancer
5) Confidence 0.19 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2241841 Disease Relevance 0.50 Pain Relevance 0
Localization of the Ki 67 protein, as well as different isoforms, could play an important role in cell cycle regulation.
Localization (Localization) of Ki 67
6) Confidence 0.15 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1410751 Disease Relevance 0.54 Pain Relevance 0
g/mL), anti-PPARG (rabbit monoclonal, Cell Signalling, New England Biolabs GmbH, Frankfurt am Main, Germany; dilution 1 : 400), anti-TP53 (mouse monoclonal IgG, clone Bp53-12 (sc-263), Santa Cruz Biotechnology Santa Cruz, Calif, USA; dilution 1 : 1000), and anti-Ki-67 (rabbit monoclonal, clone MIB1; DakoCytomation GmbH, Hamburg, Germany; dilution 1 : 10, final concentration 5 ?
Localization (dilution) of Ki-67
7) Confidence 0.15 Published 2010 Journal PPAR Research Section Body Doc Link PMC2712952 Disease Relevance 0.21 Pain Relevance 0.26
Positive nuclear staining for Ki-67 was observed.
Localization (staining) of Ki-67
8) Confidence 0.08 Published 2009 Journal J. Vet. Diagn. Invest. Section Abstract Doc Link 19564506 Disease Relevance 0.45 Pain Relevance 0.06
Modified microwave antigen retrieval in citrate buffer (pH 6.0) was used for analyzing antibodies to calretinin, CD34, and Ki-67.
Localization (calretinin) of Ki-67
9) Confidence 0.04 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2954971 Disease Relevance 0.13 Pain Relevance 0
Antibodies to S-100 protein, calretinin, vimentin, neuron-specific enolase (NSE), and Ki-67 (MIB-1) were obtained from DakoCytomation (Kyoto, Japan).
Localization (calretinin) of Ki-67 in neuron
10) Confidence 0.04 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2954971 Disease Relevance 0.22 Pain Relevance 0

General Comments

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