INT97470

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Context Info
Confidence 0.23
First Reported 2001
Last Reported 2011
Negated 0
Speculated 2
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 2.39
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (FAT1) plasma membrane (FAT1) nucleus (FAT1)
cell-cell signaling (FAT1) cytoplasm (FAT1)
Anatomy Link Frequency
fat 5
FAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 78.12 Quite High
COX-2 inhibitor 1 75.00 Quite High
tolerance 32 73.72 Quite High
Inflammation 3 49.28 Quite Low
cytokine 2 48.24 Quite Low
Restless leg syndrome 4 42.48 Quite Low
COX2 1 25.00 Low Low
Catecholamine 56 5.20 Low Low
adenocard 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 37 100.00 Very High Very High Very High
Adhesions 1 100.00 Very High Very High Very High
Frailty 11 98.32 Very High Very High Very High
Necrosis 4 93.28 High High
Obesity 37 93.04 High High
Cancer 4 92.92 High High
Aging 19 90.80 High High
Hyperinsulinism 6 89.48 High High
Colon Cancer 3 84.84 Quite High
Diabetes Mellitus 95 78.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among the subtracted cDNA fragments confirmed as differentially expressed, there were two which are known to be involved in the regulation of cell adhesion (human FAT and proto-cadherin-7).
Regulation (regulation) of FAT associated with adhesions
1) Confidence 0.23 Published 2001 Journal Oncogene Section Abstract Doc Link 11494140 Disease Relevance 0.63 Pain Relevance 0.19
Thus, it is feasible that HIIE fat loss programs are effective for producing a clinical decrease in fat (greater than 6% of fat mass) for some but not all participants.
Regulation (effective) of fat in fat
2) Confidence 0.05 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2991639 Disease Relevance 0.11 Pain Relevance 0.03
However, some studies have utilized longer programs to determine the effect of HIIE on subcutaneous and abdominal fat loss.
Spec (determine) Regulation (effect) of fat in fat
3) Confidence 0.05 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2991639 Disease Relevance 0.15 Pain Relevance 0
High-Intensity Intermittent Exercise and Fat Loss

The effect of regular aerobic exercise on body fat is negligible; however, other forms of exercise may have a greater impact on body composition.

Regulation (effect) of fat in fat
4) Confidence 0.05 Published 2011 Journal Journal of Obesity Section Title Doc Link PMC2991639 Disease Relevance 0.22 Pain Relevance 0.04
This review summarises results of research examining the effect of different forms of HIIE on fitness, insulin resistance, skeletal muscle, subcutaneous, and abdominal fat loss.

2.

Spec (examining) Regulation (effect) of fat in fat associated with insulin resistance
5) Confidence 0.05 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2991639 Disease Relevance 0.17 Pain Relevance 0
Both may also play a role in body fat distribution [37, 43, 44, 76, 77] and sarcopenia [18].
Regulation (role) of fat in fat associated with frailty
6) Confidence 0.03 Published 2011 Journal Journal of Aging Research Section Body Doc Link PMC3010636 Disease Relevance 1.11 Pain Relevance 0

General Comments

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