INT9749

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 1992
Last Reported 2010
Negated 1
Speculated 2
Reported most in Abstract
Documents 25
Total Number 26
Disease Relevance 9.96
Pain Relevance 2.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
sting 6
pollen 4
lung 2
nerve 1
edges 1
sar (Mus musculus)
Pain Link Frequency Relevance Heat
syringomyelia 82 98.86 Very High Very High Very High
Antihistamine 8 98.84 Very High Very High Very High
vagus nerve 10 97.80 Very High Very High Very High
c fibre 16 97.28 Very High Very High Very High
imagery 18 84.28 Quite High
potassium channel 2 75.00 Quite High
Inflammatory mediators 1 61.72 Quite High
Pain 30 61.28 Quite High
headache 10 30.00 Quite Low
anesthesia 7 25.00 Low Low
Disease Link Frequency Relevance Heat
Hypersensitivity 464 100.00 Very High Very High Very High
Rhinitis 20 99.98 Very High Very High Very High
Bites And Stings 200 99.84 Very High Very High Very High
Syringomyelia 82 98.86 Very High Very High Very High
Abnormal Reflex 17 96.40 Very High Very High Very High
Scoliosis 98 89.52 High High
Cancer 1 87.36 High High
Insect Bites And Stings 56 75.00 Quite High
Fever 3 75.00 Quite High
Paralysis 1 74.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If patients without any indicators of syringomyelia were regarded as genuine "idiopathic" cases, this might increase the PPV of SAR.
Spec (might) Positive_regulation (increase) of SAR associated with syringomyelia
1) Confidence 0.50 Published 2010 Journal Scoliosis Section Body Doc Link PMC2939502 Disease Relevance 1.11 Pain Relevance 0.34
We used the information about the prevalence of symptoms, calling time per day, and number of calls per day and combined it with measurements of the Specific Absorption Rate (SAR).
Positive_regulation (measurements) of SAR
2) Confidence 0.49 Published 2003 Journal Bioelectromagnetics Section Abstract Doc Link 12669297 Disease Relevance 0 Pain Relevance 0
Intravenous administration of 4-aminopyridine (0. 7 and 2.0 mg/kg i.v.), a K(+) channel blocker, which dose-dependently increased SAR activity during deflation and had no effect on P(T), abolished or attenuated the decrease in SAR activities induced by CO(2) inhalation in a dose-dependent manner.
Positive_regulation (increased) of SAR
3) Confidence 0.45 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10454467 Disease Relevance 0 Pain Relevance 0.08
Absorbers can induce a significant increase of SAR in muscle and fat near their edges.
Positive_regulation (increase) of SAR in edges
4) Confidence 0.32 Published 2001 Journal Int J Hyperthermia Section Abstract Doc Link 11347729 Disease Relevance 0.35 Pain Relevance 0.06
We investigated the safety and efficacy of omalizumab in the treatment of patients with Japanese cedar pollen-induced SAR compared to placebo.
Positive_regulation (induced) of SAR in pollen associated with rhinitis
5) Confidence 0.32 Published 2006 Journal Allergol Int Section Abstract Doc Link 17130680 Disease Relevance 0.44 Pain Relevance 0
Intravenous administration of 4-aminopyridine (0. 7 and 2.0 mg/kg i.v.), a K(+) channel blocker, which dose-dependently increased SAR activity during deflation and had no effect on P(T), abolished or attenuated the decrease in SAR activities induced by CO(2) inhalation in a dose-dependent manner.
Positive_regulation (induced) of SAR
6) Confidence 0.30 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10454467 Disease Relevance 0 Pain Relevance 0.07
Administration of ouabain (50 microg/kg) initially stimulated SAR activity during both inflation and deflation, but after 20 min, two different types of SAR responses were observed; one became silent at the peak, of inflation only, and the other maintained excitatory activity during both inflation and deflation phases.
Positive_regulation (stimulated) of SAR
7) Confidence 0.26 Published 1998 Journal Life Sci. Section Abstract Doc Link 9952289 Disease Relevance 0 Pain Relevance 0.05
METHODS: A randomized, placebo-controlled, double-blind study was conducted in 100 Japanese patients with a history of moderate-to-severe SAR induced by Japanese cedar pollens.
Positive_regulation (induced) of SAR in pollens
8) Confidence 0.19 Published 2006 Journal Allergol Int Section Body Doc Link 17130680 Disease Relevance 0.09 Pain Relevance 0
CONCLUSIONS: Omalizumab was effective and safe in the treatment of SAR induced by Japanese cedar pollen.


Positive_regulation (induced) of SAR in pollen
9) Confidence 0.19 Published 2006 Journal Allergol Int Section Body Doc Link 17130680 Disease Relevance 0 Pain Relevance 0
BACKGROUND: Seasonal allergic rhinitis (SAR) induced by Japanese cedar pollen is a substantial problem in Japan.
Positive_regulation (induced) of SAR in pollen associated with rhinitis
10) Confidence 0.19 Published 2006 Journal Allergol Int Section Abstract Doc Link 17130680 Disease Relevance 0.36 Pain Relevance 0
Increased risk of experiencing SAR to a future sting in wasp allergic patients after cessation of adequate IT was significantly associated with a SAR due to IT during the rush regimen.
Positive_regulation (Increased) of SAR in sting associated with bites and stings and hypersensitivity
11) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Abstract Doc Link PMC1208928 Disease Relevance 1.08 Pain Relevance 0
That means that the untreated patient would expect SAR to several future stings.
Positive_regulation (expect) of SAR in stings associated with bites and stings and hypersensitivity
12) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Body Doc Link PMC1208928 Disease Relevance 0.37 Pain Relevance 0
According to other studies the following symptoms and signs have been found to be risk factors for experiencing SAR at a future sting after cessation of adequate IT [13]: severity of pre-treatment reaction, safety and efficacy of IT, duration of IT, and high sensitivity with the IC test.
Positive_regulation (experiencing) of SAR in sting associated with bites and stings and hypersensitivity
13) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Body Doc Link PMC1208928 Disease Relevance 0.77 Pain Relevance 0
However, the adequately treated wasp allergic patients experienced a SAR to sting after cessation of IT more frequently than has been found in other studies [12].
Positive_regulation (experienced) of SAR in sting associated with bites and stings and hypersensitivity
14) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Body Doc Link PMC1208928 Disease Relevance 0.78 Pain Relevance 0
The percentage of patients experiencing a SAR during incremental dosing is higher.
Positive_regulation (experiencing) of SAR associated with hypersensitivity
15) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Body Doc Link PMC1208928 Disease Relevance 0.16 Pain Relevance 0.05
Increased risk of experiencing SAR to a future sting in wasp allergic patients after cessation of adequate IT was significantly associated with a SAR due to IT during the rush regimen.
Positive_regulation (experiencing) of SAR in sting associated with bites and stings and hypersensitivity
16) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Abstract Doc Link PMC1208928 Disease Relevance 1.08 Pain Relevance 0
None of the bee allergic patients experienced a SAR after cessation of IT.
Positive_regulation (experienced) of SAR associated with hypersensitivity
17) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Body Doc Link PMC1208928 Disease Relevance 1.69 Pain Relevance 0
Table 11 lists a comparison between those who did not experience any reaction to a sting after cessation of adequate IT (group A) and those who experienced a SAR (group B) in patients allergic to common wasp.
Positive_regulation (experienced) of SAR in sting associated with bites and stings and hypersensitivity
18) Confidence 0.17 Published 2005 Journal Clin Mol Allergy Section Body Doc Link PMC1208928 Disease Relevance 1.45 Pain Relevance 0
Administration of veratridine (40 microg/kg) stimulated SAR activity but did not significantly alter tracheal pressure.
Neg (not) Positive_regulation (stimulated) of SAR
19) Confidence 0.17 Published 1998 Journal Life Sci. Section Abstract Doc Link 9952289 Disease Relevance 0 Pain Relevance 0.05
Intravenous administration of veratridine (50 microg/kg), an Na(+) channel opener, stimulated deflationary SAR activity: one maintained excitatory activity mainly during deflation and the other receptors showed a tonic discharge during both deflation and inflation.
Positive_regulation (stimulated) of SAR
20) Confidence 0.05 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11805222 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox