INT97505

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Context Info
Confidence 0.78
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 0.71
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Prrxl1) DNA binding (Prrxl1)
Anatomy Link Frequency
spinal cord 2
interneurons 2
neurons 1
ventral 1
Prrxl1 (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 5 100.00 Very High Very High Very High
Dorsal horn 4 99.04 Very High Very High Very High
substantia gelatinosa 4 98.40 Very High Very High Very High
Spinal cord 12 96.80 Very High Very High Very High
Pain 3 68.32 Quite High
Deep tissue 1 63.84 Quite High
Central nervous system 2 5.00 Very Low Very Low Very Low
Dorsal horn neuron 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 10 97.44 Very High Very High Very High
Congenital Anomalies 2 89.04 High High
Death 1 70.24 Quite High
Pain 2 68.32 Quite High
Targeted Disruption 12 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of a Prrxl1 alternative splice variant during the development of the mouse nociceptive system.
Gene_expression (Expression) of Prrxl1 associated with nociception and nociceptor
1) Confidence 0.78 Published 2009 Journal Int. J. Dev. Biol. Section Title Doc Link 19598127 Disease Relevance 0.18 Pain Relevance 0.14
DRG11, a paired homeodomain transcription factor, is expressed in both the developing dorsal horn and in sensory neurons, but not in the ventral spinal cord.
Neg (not) Gene_expression (expressed) of DRG11 in ventral associated with dorsal horn and spinal cord
2) Confidence 0.77 Published 2001 Journal Neuron Section Abstract Doc Link 11498051 Disease Relevance 0.16 Pain Relevance 0.31
This study addresses the role played by DRG11, a transcription factor expressed in the spinal area of projection of small-diameter DRG neurons, in the development of the primary afferent system.
Gene_expression (expressed) of DRG11 in neurons
3) Confidence 0.77 Published 2006 Journal Mol. Cell. Neurosci. Section Abstract Doc Link 16978876 Disease Relevance 0.24 Pain Relevance 0.03
RESULTS: The amount of Prrxl1 was higher than that of the Prrxl1-b isoform both in the DRG and the spinal cord.
Gene_expression (amount) of Prrxl1-b in spinal cord
4) Confidence 0.68 Published 2009 Journal Int. J. Dev. Biol. Section Body Doc Link 19598127 Disease Relevance 0 Pain Relevance 0
RESULTS: The amount of Prrxl1 was higher than that of the Prrxl1-b isoform both in the DRG and the spinal cord.
Gene_expression (amount) of Prrxl1 in spinal cord
5) Confidence 0.68 Published 2009 Journal Int. J. Dev. Biol. Section Body Doc Link 19598127 Disease Relevance 0 Pain Relevance 0
The expression patterns of Prxxl1 (DRG11), Lbxcor1(Corl1), Zic1-5, Tsh2, Sall3, Zfhx1b, Bcl11a indicate that these SSTFs are expressed in association interneurons [9], [36]–[38].
Gene_expression (expression) of DRG11 in interneurons
6) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0.06 Pain Relevance 0.11
The expression patterns of Prxxl1 (DRG11), Lbxcor1(Corl1), Zic1-5, Tsh2, Sall3, Zfhx1b, Bcl11a indicate that these SSTFs are expressed in association interneurons [9], [36]–[38].
Gene_expression (expressed) of DRG11 in interneurons
7) Confidence 0.35 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0.07 Pain Relevance 0.12

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