INT97546

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Context Info
Confidence 0.40
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pomc, Mc1r) pigmentation (Mc1r) generation of precursor metabolites and energy (Pomc)
extracellular space (Pomc) extracellular region (Pomc) plasma membrane (Mc1r)
Anatomy Link Frequency
stem cell 2
Pomc (Mus musculus)
Mc1r (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 2 100.00 Very High Very High Very High
antagonist 2 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Skin Cancer 2 74.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several active factors are products of developmental and other coat color genes, including stem cell factor (SCF), melanocyte-stimulating hormone (alphaMSH), and agouti signaling protein (ASP), a natural antagonist at the MSH receptor (melanocortin 1 receptor, MC1R) encoded by the agouti gene.
alphaMSH Negative_regulation (antagonist) of MC1R in stem cell associated with melanocortin 1 receptor and antagonist
1) Confidence 0.40 Published 2001 Journal Dev. Dyn. Section Abstract Doc Link 11500974 Disease Relevance 0.07 Pain Relevance 0.15
Several active factors are products of developmental and other coat color genes, including stem cell factor (SCF), melanocyte-stimulating hormone (alphaMSH), and agouti signaling protein (ASP), a natural antagonist at the MSH receptor (melanocortin 1 receptor, MC1R) encoded by the agouti gene.
alphaMSH Negative_regulation (antagonist) of melanocortin 1 receptor in stem cell associated with melanocortin 1 receptor and antagonist
2) Confidence 0.35 Published 2001 Journal Dev. Dyn. Section Abstract Doc Link 11500974 Disease Relevance 0.07 Pain Relevance 0.15

General Comments

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