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Context Info
Confidence 0.21
First Reported 2001
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.40
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il20) extracellular region (Il20)
Anatomy Link Frequency
T-cell 2
Il20 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 56 100.00 Very High Very High Very High
Inflammation 46 100.00 Very High Very High Very High
psoriasis 44 94.36 High High
Opioid 1 83.44 Quite High
antagonist 8 75.00 Quite High
mu opioid receptor 1 70.32 Quite High
Inflammatory mediators 4 48.28 Quite Low
Endogenous opioid 1 38.32 Quite Low
Multiple sclerosis 48 17.72 Low Low
rheumatoid arthritis 88 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 47 100.00 Very High Very High Very High
Targeted Disruption 4 98.92 Very High Very High Very High
Psoriasis 49 94.36 High High
Acanthosis 4 93.16 High High
Pressure And Volume Under Development 2 74.72 Quite High
Dermatitis 1 65.72 Quite High
Autoimmune Disease 33 54.84 Quite High
Calcification 1 40.92 Quite Low
Disease 69 32.28 Quite Low
Skin Diseases 2 21.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic administration of melatonin for 5 days to antigen-primed mice increased the production of pro-inflammatory cytokine IL-10 but decreased the secretion of anti-inflammatory cytokine TNF-alpha.
Positive_regulation (increased) of Gene_expression (production) of cytokine IL-10 associated with inflammation and cytokine
1) Confidence 0.21 Published 2001 Journal Mol. Cell. Biochem. Section Abstract Doc Link 11506187 Disease Relevance 0.20 Pain Relevance 0.45
In this study, splenocytes from DO11.10 T-cell antigen receptor (TCR) transgenic mice activated with ovalbumin peptide preferentially produced IL-22, but not the related cytokines, IL-19, IL-20 or IL-24, after IL-23 stimulation.
Positive_regulation (stimulation) of Neg (not) Gene_expression (produced) of IL-20 in T-cell associated with targeted disruption and cytokine
2) Confidence 0.08 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2768824 Disease Relevance 1.20 Pain Relevance 0.41

General Comments

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