INT97646

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Context Info
Confidence 0.36
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 3.56
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gc) extracellular space (Gc) extracellular region (Gc)
Anatomy Link Frequency
platelet 1
Gc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 18 99.72 Very High Very High Very High
Angina 1 72.44 Quite High
Multiple sclerosis 1 51.84 Quite High
Disease Link Frequency Relevance Heat
Overdose 13 99.16 Very High Very High Very High
Hepatic Encephalopathy 20 94.12 High High
Toxicity 4 89.92 High High
Hepatotoxicity 12 89.68 High High
Acute Liver Failure 1 77.12 Quite High
Myocardial Infarction 3 75.00 Quite High
Angina 1 72.44 Quite High
Multiple Trauma 1 71.92 Quite High
Multiple Organ Failure 2 70.40 Quite High
Sepsis 1 66.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, bound Gc-globulin remained within normal levels for all patients throughout the observation period.
Gc-globulin Binding (bound) of
1) Confidence 0.36 Published 2001 Journal Liver Transpl. Section Abstract Doc Link 11510020 Disease Relevance 0.89 Pain Relevance 0.26
Temporal profile of total, bound, and free Gc-globulin after acetaminophen overdose.
Gc-globulin Binding (bound) of associated with paracetamol and overdose
2) Confidence 0.36 Published 2001 Journal Liver Transpl. Section Title Doc Link 11510020 Disease Relevance 0.57 Pain Relevance 0.38
The main function of Gc-globulin is to bind vitamin D and actin, which is released into the extracellular environment upon cell and tissue lysis.
Gc-globulin Binding (bind) of
3) Confidence 0.35 Published 2008 Journal Postepy Hig Med Dosw (Online) Section Abstract Doc Link 19002085 Disease Relevance 0.54 Pain Relevance 0.17
Serum Gc-globulin (total, actin bound, and free) levels and actin-complex ratio were measured on admission and every 12 hours until discharge.
Gc-globulin Binding (bound) of
4) Confidence 0.27 Published 2001 Journal Liver Transpl. Section Abstract Doc Link 11510020 Disease Relevance 0.56 Pain Relevance 0.35
Bound Gc-globulin is maintained at constant levels independent of total Gc-globulin levels, suggesting a balanced upregulation of the removal of bound Gc-globulin even under conditions with increased actin release.
Gc-globulin Binding (bound) of
5) Confidence 0.27 Published 2001 Journal Liver Transpl. Section Abstract Doc Link 11510020 Disease Relevance 0.67 Pain Relevance 0.07
Mechanistically, VDB protein reduces platelet aggregation and prolongs coagulation time ex vivo.
VDB protein Binding (aggregation) of in platelet
6) Confidence 0.07 Published 2010 Journal Front Biosci (Elite Ed) Section Abstract Doc Link 20515752 Disease Relevance 0.33 Pain Relevance 0.07

General Comments

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