INT97691

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Context Info
Confidence 0.26
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (REST, HDAC9) transcription factor binding (REST, HDAC9) cytoplasm (REST, HDAC9)
cytosol (REST) nucleolus (REST) intracellular (REST)
Anatomy Link Frequency
neuronal 1
REST (Homo sapiens)
HDAC9 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 2 96.08 Very High Very High Very High
Nav1.2 1 92.28 High High
Nerve growth factor 1 83.52 Quite High
Disease Link Frequency Relevance Heat
Repression 1 89.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, these studies define a novel HDAC complex that is recruited by the C-terminal repressor domain of REST to actively repress genes essential to the neuronal phenotype.
REST Binding (recruited) of HDAC in neuronal
1) Confidence 0.26 Published 2001 Journal Neuron Section Abstract Doc Link 11516394 Disease Relevance 0.09 Pain Relevance 0.23

General Comments

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