INT97709

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Context Info
Confidence 0.68
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apoe) transport (Apoe) extracellular space (Apoe)
aging (Apoe) extracellular region (Apoe) Golgi apparatus (Apoe)
Anatomy Link Frequency
astrocyte 2
Apoe (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 3 79.68 Quite High
agonist 7 56.48 Quite High
Clonidine 1 47.28 Quite Low
Serotonin 1 28.32 Quite Low
Nerve growth factor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 13 100.00 Very High Very High Very High
Disease 4 96.72 Very High Very High Very High
Pathologic Processes 1 84.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We show here that in rat primary hippocampal astrocyte cultures, dibutyryl-cAMP increased apolipoprotein E secretion with time in a dose-dependent manner (to 177% at 48 h) and that retinoic acid potentiated this effect (to 298% at 48 h).
Positive_regulation (increased) of Localization (secretion) of apolipoprotein E in astrocyte associated with disorder of lipid metabolism
1) Confidence 0.68 Published 2001 Journal Neuroscience Section Abstract Doc Link 11516830 Disease Relevance 1.02 Pain Relevance 0.07

General Comments

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