INT97716

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Context Info
Confidence 0.53
First Reported 2001
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.61
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apoe) transport (Apoe) extracellular space (Apoe)
aging (Apoe) extracellular region (Apoe) Golgi apparatus (Apoe)
Apoe (Rattus norvegicus)
Pain Link Frequency Relevance Heat
aspirin 4 98.90 Very High Very High Very High
Kinase C 6 98.84 Very High Very High Very High
cINOD 7 98.64 Very High Very High Very High
agonist 14 87.76 High High
Clonidine 2 78.56 Quite High
Serotonin 2 59.60 Quite High
Nerve growth factor 2 25.36 Quite Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 28 100.00 Very High Very High Very High
Disease 14 87.84 High High
Pathologic Processes 2 75.60 Quite High
INFLAMMATION 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to these results, indomethacin and aspirin treatment failed to induce any significant changes in apoE mRNA levels.
Transcription (levels) of apoE associated with aspirin
1) Confidence 0.53 Published 2003 Journal Eur. J. Neurosci. Section Abstract Doc Link 14511323 Disease Relevance 0.51 Pain Relevance 0.69
Dibutyryl-cAMP also gave a rapid, albeit transient, increase of apolipoprotein E mRNA expression (to 200% at 1 h).
Transcription (expression) of apolipoprotein E associated with disorder of lipid metabolism
2) Confidence 0.52 Published 2001 Journal Neuroscience Section Abstract Doc Link 11516830 Disease Relevance 1.06 Pain Relevance 0.27
In contrast, the protein kinase C activator phorbol 12-myristate 13-acetate decreased both apolipoprotein E secretion (to 59% at 48 h) and mRNA expression (to 22% at 1 h).
Transcription (expression) of apolipoprotein E associated with kinase c and disorder of lipid metabolism
3) Confidence 0.52 Published 2001 Journal Neuroscience Section Abstract Doc Link 11516830 Disease Relevance 1.04 Pain Relevance 0.40

General Comments

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