INT97796

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Context Info
Confidence 0.20
First Reported 2000
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IRF6) nucleus (IRF6) DNA binding (IRF6)
cytoplasm (IRF6)
Anatomy Link Frequency
mononuclear cells 2
IRF6 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 2 95.08 Very High Very High Very High
antagonist 7 92.48 High High
agonist 1 86.24 High High
Inflammation 16 70.48 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
Kinase C inhibitor 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 68 92.40 High High
INFLAMMATION 16 70.48 Quite High
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Metabolic Syndrome 2 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Overweight 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the work that is presented here, we show in detail the principal activation regulation pathways of the LPS induced secretion of TNFalpha.
Regulation (regulation) of Localization (secretion) of LPS
1) Confidence 0.20 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2819999 Disease Relevance 0.25 Pain Relevance 0
Furthermore, chlorpromazine did not affect the antagonistic activity of RsLPS or E5564 on IL-6 generation by peripheral blood mononuclear cells.
Neg (not) Regulation (affect) of Localization (generation) of RsLPS in mononuclear cells
2) Confidence 0.01 Published 2000 Journal J. Endotoxin Res. Section Abstract Doc Link 11521069 Disease Relevance 0.07 Pain Relevance 0.50

General Comments

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