INT97855

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Context Info
Confidence 0.04
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 1.65
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SDCBP) endoplasmic reticulum (SDCBP) plasma membrane (SDCBP)
cytoskeleton (SDCBP) nucleus (SDCBP) cytoplasm (SDCBP)
Anatomy Link Frequency
14.1 1
SDCBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 12 75.00 Quite High
Calcium channel 4 75.00 Quite High
Percutaneous transluminal coronary angioplasty 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 4 99.50 Very High Very High Very High
Stress 6 98.76 Very High Very High Very High
Cv General 3 Under Development 8 75.00 Quite High
Spasticity 4 75.00 Quite High
Stable Angina Pectoris 4 73.24 Quite High
Myocardial Infarction 4 72.16 Quite High
Increased Venous Pressure Under Development 2 66.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum MDA-LDL was elevated before the procedure (99.3 +/- 48.9 U/l) in the control group and significantly decreased immediately after the procedure(61.7 +/- 26.2 U/l).
Negative_regulation (decreased) of MDA-LDL
1) Confidence 0.04 Published 2001 Journal J Cardiol Section Body Doc Link 11525110 Disease Relevance 0.12 Pain Relevance 0
Serum MDA-LDL was elevated above the normal range before the procedure in both groups(MI group 104.7 +/- 52.0 U/l, AP group 99.7 +/- 42.8 U/l), and significantly decreased immediately after the procedure(MI group 61.3 +/- 25.6 U/l, AP group 62.0 +/- 29.6 U/l), but there were no significant differences between the two groups.
Negative_regulation (decreased) of MDA-LDL
2) Confidence 0.04 Published 2001 Journal J Cardiol Section Body Doc Link 11525110 Disease Relevance 0.15 Pain Relevance 0
The results showed that improvement of lipid metabolism, especially an increase of HDL cholesterol level and a reduction of MDA-LDL, may inhibit vascular contractility.
Negative_regulation (reduction) of MDA-LDL associated with disorder of lipid metabolism
3) Confidence 0.01 Published 2008 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 18594477 Disease Relevance 0.63 Pain Relevance 0.27
Furthermore, a significant decrease of the malondialdehyde-modified low-density lipoprotein (MDA-LDL) level, a marker of oxidative stress, was also observed (-22.6 +/- 14.1%, P < 0.01 versus baseline) in this group.
Negative_regulation (decrease) of MDA-LDL in 14.1 associated with stress
4) Confidence 0.01 Published 2008 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 18594477 Disease Relevance 0.75 Pain Relevance 0.35

General Comments

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