INT97901

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Context Info
Confidence 0.24
First Reported 2001
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.56
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FGFR1) extracellular region (FGFR1) cytoplasmic membrane-bounded vesicle (FGFR1)
plasma membrane (FGFR1) nucleus (FGFR1) cytoplasm (FGFR1)
Anatomy Link Frequency
lymphocyte 1
fibroblast 1
uterine 1
FGFR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 6 100.00 Very High Very High Very High
Dismenorea 3 97.60 Very High Very High Very High
palliative 1 84.68 Quite High
headache 5 80.80 Quite High
cva 3 46.12 Quite Low
positron emission tomography 1 34.08 Quite Low
lidocaine 1 22.88 Low Low
ischemia 2 12.56 Low Low
Inflammation 3 9.96 Low Low
imagery 4 8.20 Low Low
Disease Link Frequency Relevance Heat
Necrosis 1 99.82 Very High Very High Very High
Cancer 1 99.64 Very High Very High Very High
Uterine Hemorrhage 1 99.52 Very High Very High Very High
Moyamoya Disease 26 98.46 Very High Very High Very High
Reprotox - General 3 1 97.68 Very High Very High Very High
Disease 9 96.00 Very High Very High Very High
Adhesions 1 95.68 Very High Very High Very High
Paresis 3 90.56 High High
Epilepsy 2 84.72 Quite High
Myelofibrosis 5 83.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Women with leiomyoma-related abnormal uterine bleeding have local dysregulation of bFGF and its type 1 receptor (FGF-R).
Regulation (dysregulation) of FGF-R in uterine associated with uterine hemorrhage
1) Confidence 0.24 Published 2001 Journal Menopause Section Abstract Doc Link 11528364 Disease Relevance 0.27 Pain Relevance 0.26
By so taking into account between-group heterogeneity, Welch-SAM identified a set of up regulated genes that were not detected by t-SAM.
Regulation (regulated) of Welch-SAM
2) Confidence 0.12 Published 2002 Journal BMC Genomics Section Body Doc Link PMC137578 Disease Relevance 0.06 Pain Relevance 0
Although the etiology of moyamoya disease is still not known, it is considered to be multifactorial condition that is affected by elements such as vascular growth factors, cytokines, basic-fibroblast growth factor or genetic abnormality (11-15).
Regulation (affected) of basic-fibroblast growth factor in fibroblast associated with moyamoya disease and cytokine
3) Confidence 0.04 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2729958 Disease Relevance 1.16 Pain Relevance 0.20
SAM is very sensitive to noisy data, which should be removed a priori.


Regulation (sensitive) of SAM
4) Confidence 0.03 Published 2002 Journal BMC Bioinformatics Section Body Doc Link PMC126253 Disease Relevance 0 Pain Relevance 0
Current data suggest that the action of thalidomide is related to several different mechanisms, including suppression of tumor necrosis factor, effects on basic fibroblast growth factor, vascular endothelial growth factor, interleukins and interferons, downregulation of selected cell surface adhesion molecules, and changes in the lymphocyte subsets.
Regulation (effects) of basic fibroblast growth factor in lymphocyte associated with necrosis, cancer and adhesions
5) Confidence 0.02 Published 2004 Journal Eur. J. Haematol. Section Abstract Doc Link 14962263 Disease Relevance 1.07 Pain Relevance 0.08

General Comments

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