INT97974

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Context Info
Confidence 0.65
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.14
Pain Relevance 2.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
spinal cord 1
cornea 1
ciliary body 1


Pain Term Frequency Confidence Heat
Serotonin 14 100.00 Very High Very High Very High
Pain 6 98.88 Very High Very High Very High
Spinal cord 3 97.72 Very High Very High Very High
Analgesic 4 91.28 High High
sSRI 20 86.84 High High
antidepressant 10 84.76 Quite High
depression 16 83.28 Quite High
Pain management 1 81.76 Quite High
tetrodotoxin 1 78.08 Quite High
agonist 4 77.52 Quite High
Disease Term Frequency Confidence Heat
Pain 4 98.88 Very High Very High Very High
Depression 16 83.28 Quite High
Overdose 24 80.72 Quite High
Depressive Disorder 2 61.24 Quite High
Mental Disorders 2 59.16 Quite High
Glaucoma 72 50.00 Quite Low
Disease 6 42.24 Quite Low
Optic Disorders 2 38.56 Quite Low
Ocular Injury 4 5.00 Very Low Very Low Very Low
Retina Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both N-methyl-D-aspartate (NMDA) and serotonin (5-HT) receptors contribute to the generation of rhythmic motor patterns in the rat spinal cord.
Gene_expression (contribute) of serotonin (5-HT) receptors in spinal cord associated with serotonin and spinal cord
1) Confidence 0.65 Published 2001 Journal J. Neurophysiol. Section Abstract Doc Link 11535663 Disease Relevance 0 Pain Relevance 0.35
There are gene polymorphisms changing the expression or activation of the serotonin (5-HT) receptors, which are associated with pain.
Gene_expression (expression) of serotonin (5-HT) receptors associated with pain and serotonin
2) Confidence 0.58 Published 2009 Journal Masui Section Abstract Doc Link 19764436 Disease Relevance 0.18 Pain Relevance 0.59
Furthermore, it is reported that Serotonin (5-HT) receptors are present at a higher concentration in mammalian ciliary body and cornea than in non-mammalian species [7].
Gene_expression (present) of Serotonin (5-HT) receptors in cornea associated with serotonin
3) Confidence 0.58 Published 2005 Journal BMC Ophthalmol Section Body Doc Link PMC1262727 Disease Relevance 0.48 Pain Relevance 0.63
Furthermore, it is reported that Serotonin (5-HT) receptors are present at a higher concentration in mammalian ciliary body and cornea than in non-mammalian species [7].
Gene_expression (present) of Serotonin (5-HT) receptors in ciliary body associated with serotonin
4) Confidence 0.20 Published 2005 Journal BMC Ophthalmol Section Body Doc Link PMC1262727 Disease Relevance 0.48 Pain Relevance 0.63

General Comments

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