INT98002

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Context Info
Confidence 0.10
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) plasma membrane (Oprm1) signal transducer activity (Oprm1)
Anatomy Link Frequency
spinal cord 2
Oprm1 (Mus musculus)
P9Ehs1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 6 100.00 Very High Very High Very High
narcan 6 99.98 Very High Very High Very High
agonist 4 99.96 Very High Very High Very High
antagonist 2 99.80 Very High Very High Very High
mu opioid receptor 2 98.80 Very High Very High Very High
Spinal cord 3 96.96 Very High Very High Very High
Enkephalin 1 71.12 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest that chronic treatment with an mu-opioid receptor antagonist naloxone leads to the supersensitivity to activate G-protein by mu-opioid receptor agonists with an increase in mu-opioid receptors in membranes of the mouse spinal cord.
Positive_regulation (leads) of mu-opioid receptor Positive_regulation (activate) of G-protein in spinal cord associated with antagonist, mu opioid receptor, agonist, narcan, opioid receptor and spinal cord
1) Confidence 0.10 Published 2001 Journal Brain Res. Section Abstract Doc Link 11549382 Disease Relevance 0 Pain Relevance 1.00

General Comments

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