INT98037

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Context Info
Confidence 0.05
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pdpk1) cytoplasmic membrane-bounded vesicle (Pdpk1) plasma membrane (Pdpk1)
nucleus (Pdpk1) kinase activity (Pdpk1) cytoplasm (Pdpk1)
Anatomy Link Frequency
dorsal root 2
Pdpk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C inhibitor 1 100.00 Very High Very High Very High
antagonist 1 98.12 Very High Very High Very High
agonist 1 91.28 High High
substance P 2 87.56 High High
Spinal cord 1 84.24 Quite High
spinal dorsal horn 1 78.08 Quite High
nociceptor 4 75.00 Quite High
Dorsal horn neuron 1 75.00 Quite High
Dorsal horn 2 58.80 Quite High
Disease Link Frequency Relevance Heat
Nociception 5 95.94 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nociceptive afferent (dorsal root) stimulation of isolated spinal cords (10-14 day old rats) evoked a 'prolonged' excitatory polysynaptic potential (DR-EPSP) that was attenuated (P < 0.05) by: the protein kinase A inhibitor, Rp-cAMP; the protein kinase C inhibitor, bisindolymaleimide I; and the selective NK1R antagonist, GR82334.
Negative_regulation (inhibitor) of Negative_regulation (inhibitor) of protein kinase in dorsal root associated with nociception, antagonist and kinase c inhibitor
1) Confidence 0.05 Published 2001 Journal Eur. J. Neurosci. Section Abstract Doc Link 11553293 Disease Relevance 0.26 Pain Relevance 0.52

General Comments

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