INT98061

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.28
Pain Relevance 1.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Rac1) enzyme binding (Rac1) GTPase activity (Rac1)
cytoplasm (Rac1) cell proliferation (Rac1) cell motility (Rac1)
Anatomy Link Frequency
neurons 2
Rac1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Thermal hyperalgesia 1 99.92 Very High Very High Very High
Brush evoked pain 1 98.92 Very High Very High Very High
hyperexcitability 2 96.92 Very High Very High Very High
Pain 3 93.84 High High
Dorsal horn 3 84.08 Quite High
Neuropathic pain 5 75.00 Quite High
Spinal cord 2 75.00 Quite High
Botox 2 63.12 Quite High
Action potential 1 56.16 Quite High
neuralgia 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Cerebral Palsy 2 100.00 Very High Very High Very High
Hyperalgesia 1 99.92 Very High Very High Very High
Muscle Weakness 1 99.84 Very High Very High Very High
Skin Appendage Disease 3 99.60 Very High Very High Very High
Frailty 10 99.28 Very High Very High Very High
Neuropathic Pain 6 98.92 Very High Very High Very High
Injury 1 97.52 Very High Very High Very High
Spasticity 1 95.32 Very High Very High Very High
Pain 3 93.84 High High
Contusions 1 80.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of the small GTP-binding protein Rac1 ameliorated post-SCI changes in spine morphology, attenuated injury-induced hyperexcitability of wide-dynamic range neurons, and progressively increased pain thresholds over a 3 d period.
Negative_regulation (Inhibition) of Rac1 Binding (binding) of in neurons associated with pain, injury, frailty and hyperexcitability
1) Confidence 0.43 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 19052208 Disease Relevance 1.55 Pain Relevance 0.92
[Treatment of the motor cerebral palsy child with botulinum toxin A: mode of action, injection places in management].
Negative_regulation (places) of botulinum toxin Binding ([Treatment) of associated with cerebral palsy
2) Confidence 0.34 Published 2002 Journal Arch Pediatr Section Title Doc Link 12387176 Disease Relevance 0.29 Pain Relevance 0.08
Focal palmar hyperhidrosis can be effectively abolished by intradermal injections with botulinum toxin.
Negative_regulation (abolished) of botulinum toxin Binding (injections) of associated with skin appendage disease
3) Confidence 0.15 Published 2001 Journal Eur. J. Neurol. Section Abstract Doc Link 11554908 Disease Relevance 0.44 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox