INT98120

Context Info Confidence 0.04 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.29 Pain Relevance 0.39

signal transduction (Ngf) extracellular space (Ngf) extracellular region (Ngf) plasma membrane (SCN10A) transmembrane transport (SCN10A)

Anatomy Link Frequency nerve 1 Ngf (Mus musculus) SCN10A (Homo sapiens)

Pain Link Frequency Relevance Heat Nerve growth factor 3 100.00 sodium channel 2 99.66 Pain 2 95.96 Inflammation 1 94.88 Trk A 1 60.88 Causalgia 1 46.80 nociceptor 2 25.00 Neuropeptide 1 25.00

Disease Link Frequency Relevance Heat Pain 2 95.96 Nervous System Injury 1 95.52 INFLAMMATION 1 94.88 Causalgia 1 46.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The sodium channels SNS/PN3 and NaN/SNS2 are regulated by the neurotrophic factors-nerve growth factor (NGF) and glial-derived neurotrophic factor (GDNF), and may play an important role in the development of pain after nerve injury or inflammation.

NGF Regulation (regulated) of SNS in nerve associated with pain, nervous system injury, inflammation, nerve growth factor and sodium channel

1) Confidence 0.04 Published 2001 Journal Eur J Pain Section Abstract Doc Link 11558987 Disease Relevance 0.29 Pain Relevance 0.39

General Comments

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