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Context Info
Confidence 0.72
First Reported 2001
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.84
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (FURIN) peptidase activity (FURIN) extracellular space (FURIN)
aging (FURIN) Golgi apparatus (FURIN) plasma membrane (FURIN)
Anatomy Link Frequency
cleavage 1
FURIN (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 43 94.48 High High
Pain 11 86.52 High High
Osteoarthritis 1 82.88 Quite High
rheumatoid arthritis 1 82.24 Quite High
depression 1 38.72 Quite Low
Potency 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 43 94.48 High High
Bacillus Anthracis Infection 57 89.56 High High
Pain 8 86.52 High High
Osteoarthritis 1 82.88 Quite High
Rheumatoid Arthritis 1 82.24 Quite High
Pressure And Volume Under Development 1 81.16 Quite High
Infection 7 69.12 Quite High
Sprains And Strains 2 68.48 Quite High
Death 10 65.00 Quite High
Anaerobic Bacterial Infections 6 51.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PACE is targeted for adults who are not currently exercising regularly and allows for variation in course content and scheduling.
Localization (targeted) of PACE
1) Confidence 0.72 Published 2005 Journal Prev Chronic Dis Section Body Doc Link PMC1364520 Disease Relevance 0.69 Pain Relevance 0.34
The MMEL2 protein has the structural characteristics of type II transmembrane proteins, although the presence of a furin-like cleavage site in the ectodomain suggests that it may be released into the medium following proteolytic cleavage.
Localization (released) of furin in cleavage
2) Confidence 0.68 Published 2001 Journal DNA Cell Biol. Section Abstract Doc Link 11560781 Disease Relevance 0.09 Pain Relevance 0.09
The path leading from PA binding to cells via TEM-8 [5] or CMG2 [6], furin processing, heptamer formation, LF or EF binding to heptamer, or the translocation of EF/LF to the cytosol provides multiple sites for molecular intervention.
Localization (translocation) of furin
3) Confidence 0.09 Published 2004 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC420254 Disease Relevance 1.06 Pain Relevance 0

General Comments

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