INT9815

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Context Info
Confidence 0.29
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 9
Disease Relevance 3.54
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (FFAR1) plasma membrane (FFAR1) signal transducer activity (FFAR1)
Anatomy Link Frequency
plasma 2
leg 1
lobes 1
FFAR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
TRP channel 1 94.12 High High
cINOD 1 86.48 High High
Inflammation 17 75.00 Quite High
addiction 20 69.52 Quite High
anesthesia 3 60.92 Quite High
Kinase C 3 33.64 Quite Low
fibrosis 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mental Disorders 456 100.00 Very High Very High Very High
Intrauterine Growth Retardation 9 96.76 Very High Very High Very High
Psychosis 40 90.44 High High
Repression 4 88.72 High High
INFLAMMATION 17 86.24 High High
Disease 21 82.96 Quite High
Fatty Liver 63 81.92 Quite High
Nash(non-alcoholic Steatohepatitis) 27 76.40 Quite High
Obsessive-compulsive Disorder 40 72.96 Quite High
Liver Disease 18 72.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Free will may be defined in many ways, but time after time, the central question is, does this specific concept of free will enable us to explain our moral intuitions?
free will Binding (intuitions) of
1) Confidence 0.29 Published 2010 Journal Theor Med Bioeth Section Body Doc Link PMC2975916 Disease Relevance 0.44 Pain Relevance 0.03
In order to get a clearer view on the relationship between mental disorder and (a loss of) freedom, in this article, I will explore the link between mental disorder and free will.
free will Binding (link) of associated with mental disorders
2) Confidence 0.29 Published 2010 Journal Theor Med Bioeth Section Abstract Doc Link PMC2975916 Disease Relevance 0.83 Pain Relevance 0
And in fact, not only determinism but also indeterminism appears to be problematic for free will, for what room would be left for free will, if everything happened by chance?
free will Binding (left) of
3) Confidence 0.29 Published 2010 Journal Theor Med Bioeth Section Body Doc Link PMC2975916 Disease Relevance 0 Pain Relevance 0
The proportion of label associated with FFA and triglycerides did not vary with time, between lobes, or between control and IUGR fetuses.
FFA Binding (associated) of in lobes associated with intrauterine growth retardation
4) Confidence 0.28 Published 1992 Journal Pediatr. Res. Section Abstract Doc Link 1437398 Disease Relevance 0.69 Pain Relevance 0.06
He states that “the law recognizes that insanity compromises free will, and classifies someone without free will as legally not responsible for his or her actions…” [25, p. 206].
free will Binding (recognizes) of
5) Confidence 0.28 Published 2010 Journal Theor Med Bioeth Section Body Doc Link PMC2975916 Disease Relevance 0.23 Pain Relevance 0
The possibility that changes in PDK4 protein expression may have mediated the observed association between muscle glycogen and PDH regulation as well as between plasma FFA and PDH regulation is supported by the observation that the highest PDH activation and largest dephosphorylation occurred in the leg and trial with lowest PDK4 protein expression.
FFA Binding (association) of in leg
6) Confidence 0.04 Published 2010 Journal Diabetes Section Body Doc Link PMC2797931 Disease Relevance 0.08 Pain Relevance 0
Thus, the impact on PDH regulation associated with low muscle glycogen and elevated plasma FFA was not additive, which may suggest that a similar underlying mechanism could be involved in exerting this effect on PDHa activity.
FFA Binding (associated) of in plasma
7) Confidence 0.04 Published 2010 Journal Diabetes Section Body Doc Link PMC2797931 Disease Relevance 0.09 Pain Relevance 0
However, FFA exerts complex and multifaceted actions on ion transport systems and, in most instances, a molecular understanding of these FFA-dependent modulations is lacking.
FFA Binding (understanding) of
8) Confidence 0.02 Published 2009 Journal Neuropharmacology Section Abstract Doc Link 19233217 Disease Relevance 0.16 Pain Relevance 0.17
is a true sensor of plasma FFA levels by interacting with and stimulating the expression of lpin2 and St3gal5 genes after fasting [153].
FFA Binding (interacting) of in plasma
9) Confidence 0.01 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 1.02 Pain Relevance 0.03

General Comments

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