INT98171

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Context Info
Confidence 0.23
First Reported 2001
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (DLL4) signal transduction (DLL4) plasma membrane (DLL4)
Anatomy Link Frequency
embryonic kidney 1
DLL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 1 100.00 Very High Very High Very High
antagonist 2 99.92 Very High Very High Very High
agonist 19 99.42 Very High Very High Very High
Gabapentin 2 97.40 Very High Very High Very High
Calcium channel 3 86.68 High High
Enkephalin 1 75.84 Quite High
MU agonist 1 75.00 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Tics 1 53.68 Quite High
Bordatella Infection 1 50.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In human embryonic kidney 293 cells, the alpha(2)delta-4 subunit associated with Ca(V)1.2 and beta(3) subunits and significantly increased Ca(V)1.2/beta(3)-mediated Ca(2+) influx.
delta-4 Binding (associated) of in embryonic kidney
1) Confidence 0.23 Published 2002 Journal Mol. Pharmacol. Section Abstract Doc Link 12181424 Disease Relevance 0 Pain Relevance 0.30
This study assessed the effects of short-term treatment (30-min) with inverse agonists on receptor protein levels and on the ability of agonists, inverse agonists, and neutral antagonists to bind to the human delta-opioid receptor (h delta OR).
h delta OR Binding (bind) of associated with antagonist, agonist and opioid receptor
2) Confidence 0.15 Published 2001 Journal Mol. Pharmacol. Section Abstract Doc Link 11562445 Disease Relevance 0.10 Pain Relevance 0.71

General Comments

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